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Gene Polymorphism of Taste Receptors and Circulating Endocannabinoids in Normal Weight and Obese Subjects

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT02729584
Recruitment Status : Completed
First Posted : April 6, 2016
Last Update Posted : April 6, 2016
Azienda Ospedaliera Brotzu
Information provided by (Responsible Party):
Sebastiano Banni, University of Cagliari

Brief Summary:
The study aims at evaluating in normal weight and obese subjects those factors such as taste sensitivity and circulating endocannabinoids in influencing dietary choice and thereby lipid and energy metabolism in order to design personalized nutritional strategies.

Condition or disease
Nutritional Physiological Phenomena

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Study Type : Observational
Actual Enrollment : 110 participants
Observational Model: Cohort
Time Perspective: Prospective
Study Start Date : April 2013
Actual Primary Completion Date : June 2015
Actual Study Completion Date : September 2015

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Nutrition

Normal weight

Primary Outcome Measures :
  1. Endocannabinoid plasma levels [ Time Frame: 1 year ]

Information from the National Library of Medicine

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Ages Eligible for Study:   20 Years to 70 Years   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Probability Sample
Study Population
White Caucasians

Inclusion Criteria:

  • Body Mass Index (BMI), range for normal weight subjects 17.5-24.95, for obese subjects 29.6-52.20
  • No intake of nutritional supplements for at least six months before the trial

Exclusion Criteria:

  • major diseases (diabetes, kidney disease, etc.),
  • pregnancy or lactation;
  • food allergies;
  • the use of medications that interfere with taste or smell (e.g., steroids, antihistamines, certain antidepressants).
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Responsible Party: Sebastiano Banni, Professor, University of Cagliari Identifier: NCT02729584    
Other Study ID Numbers: Cagliari
First Posted: April 6, 2016    Key Record Dates
Last Update Posted: April 6, 2016
Last Verified: March 2016
Individual Participant Data (IPD) Sharing Statement:
Plan to Share IPD: No