Impact of Helminth Infections During Pregnancy on Humoral Vaccine Immunogenicity in Infants
|ClinicalTrials.gov Identifier: NCT02714348|
Recruitment Status : Unknown
Verified March 2016 by Meral Esen, Centre de Recherche Médicale de Lambaréné.
Recruitment status was: Active, not recruiting
First Posted : March 21, 2016
Last Update Posted : March 21, 2016
Helminth infection is associated with low vaccine immunogenicity. Pregnant women are particularly sensitive to helminth infection.
Since most vaccines are given shortly after birth, an effect of parasites on infant immunogenicity is of particular concern. Therefore, within this study the investigators aim to investigate if maternal infection influences vaccine immunogenicity in the newborn.
|Condition or disease||Intervention/treatment|
|Maternal Infection Affecting Newborn||Other: Effect of helminth infection on vaccine immunogenicity|
|Study Type :||Observational|
|Estimated Enrollment :||323 participants|
|Official Title:||Impact of Helminth Infections During Pregnancy on Humoral Vaccine Immunogenicity in Infants|
|Study Start Date :||February 2014|
|Estimated Primary Completion Date :||September 2016|
|Estimated Study Completion Date :||September 2016|
- Other: Effect of helminth infection on vaccine immunogenicity
- Difference in Immunoglobulin G (IgG) concentration against EPI vaccine Ags of infants born to helminth infected mothers and non infected mothers at the age of nine months and 12 months [ Time Frame: 12 months of observation ]
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02714348
|Study Director:||Akim A Adegnika, Md, PhD||Centre de Recherche Médicale de Lambaréné|