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Influence of Physical Exercise on Semen Quality

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ClinicalTrials.gov Identifier: NCT02683057
Recruitment Status : Recruiting
First Posted : February 17, 2016
Last Update Posted : February 12, 2020
Sponsor:
Collaborator:
Instituto Valenciano de Infertilidad, IVI VALENCIA
Information provided by (Responsible Party):
IVI Bilbao

Brief Summary:

Our study addresses a previously selected population or by physical activity but not for semen quality semen donor candidates donation program within the clinic.

Total physical activity was analyzed according to the universally accepted international physical activity questionnaire (IPAQ) The existence of confounding factors associated She purge age, snuff, weight, BMI, alcohol, drugs, type of sport and associated blood parameters determinations will be made to exercise.


Condition or disease Intervention/treatment
Sexual Abstinence Other: International Physical Activity Questionnaire (IPAQ)

Detailed Description:

The level of physical activity recommended great unknown and its influence from the therapeutic point of view to improve semen quality.

For it will be held:

  • 3 groups of physical activity are established, according to their score in the IPAQ: High, minimum of physical activity between > 1500 MET week Moderate: minimum of physical activity of between 600- 1500 MET week Low : until < 600 MET week
  • Implementation of a double analysis: Seminal and hormonal
  • Standardization of confounding factors associated with the individual

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Study Type : Observational
Estimated Enrollment : 432 participants
Observational Model: Cohort
Time Perspective: Prospective
Official Title: Influence of Physical Exercise on Semen Quality
Study Start Date : May 2015
Actual Primary Completion Date : March 2019
Estimated Study Completion Date : June 2020

Resource links provided by the National Library of Medicine


Group/Cohort Intervention/treatment
IPAQ HIgh
Excessive physical activity:IPAQ quantifying the activity physical according vigorous intensity activities at least 3 days per week adding a minimum total physical activity of at least 1500MET-minutes / week or 7 or more days any combination of walking, moderate intensity or vigorous intensity activities a total minimum of physical activity of at least 3,000 MET-minutes / week
Other: International Physical Activity Questionnaire (IPAQ)
all candidates for sperm donors clinic IVI IVI Bilbao and Valencia were will provide the international physical activity questionnaire (IPAQ) attached to analyze the total physical activity. This will be self-completed questionnaire beforeSperm donation. (Appendix 1) Age, snuff, weight, BMI, alcohol, drug use and the type of sport that practices will be analyzed: Additionally a tab for each donor collecting the existence of associated factors be drawn. (Appendix 2)

IPAQ Moderate
Ideal Physical activity: IPAQ quantifying the activity physical according 3 days or more of vigorous intensity physical activity at least 20 minutes per day or 5 or more days of moderate intensity and / or walk at least 30 minutes per day or 5 or more days of any combination of walking, moderate-intensity activity and activity vigorous intensity for a total minimum of physical activity of at least 600 MET-minutes / week.
Other: International Physical Activity Questionnaire (IPAQ)
all candidates for sperm donors clinic IVI IVI Bilbao and Valencia were will provide the international physical activity questionnaire (IPAQ) attached to analyze the total physical activity. This will be self-completed questionnaire beforeSperm donation. (Appendix 1) Age, snuff, weight, BMI, alcohol, drug use and the type of sport that practices will be analyzed: Additionally a tab for each donor collecting the existence of associated factors be drawn. (Appendix 2)

IPAQ Low
IPAQ quantifying the activity physical according Insufficient physical activity: Individuals who can not put on the criteria of the above categories.
Other: International Physical Activity Questionnaire (IPAQ)
all candidates for sperm donors clinic IVI IVI Bilbao and Valencia were will provide the international physical activity questionnaire (IPAQ) attached to analyze the total physical activity. This will be self-completed questionnaire beforeSperm donation. (Appendix 1) Age, snuff, weight, BMI, alcohol, drug use and the type of sport that practices will be analyzed: Additionally a tab for each donor collecting the existence of associated factors be drawn. (Appendix 2)




Primary Outcome Measures :
  1. Ascertain the influence of physical activity in sperm quality to candidates for sperm donors in the donation program according to the universally accepted questionnaire International physical activity (IPAQ) [ Time Frame: 2 years ]

    Semen parameters will be evaluated according to WHO criteria blinded on clinical and data analyst.

    International Physical Activity Questionnaire (IPAQ) offers before sperm donation quantifying the activity "walk", "activities of moderate intensity" and "vigorous intensity activities" assigned to each activity about energy requirements defined in METs, being multiples of the rate of metabolic rate equivalent to kilocalories for a 60 kg.

    The median and interquartile range (between Q1 and Q3) is calculated for walking (W), activities of moderate intensity (M), activities of vigorous intensity (V) and a combined result of total physical activity. All results must be expressed as continuous METminutos / week.



Secondary Outcome Measures :
  1. Existence of confounding factors associated with physical activity [ Time Frame: 2 years ]

    The existence of confounding factors such as age, tobacco, weight, BMI, alcohol, drugs, type of sport will be cleaned and blood parameters associated with physical activity will be defined.

    A data tab/sheet for each donor was made . The existence of related factors such as age, tobacco, weight, BMI, alcohol, drug and the type of sport exercised were been analysed.

    It categorizes the population into quartiles depending on their activity and determine which is which is associated with a better seminal quality the same debugging is made confounding previously mentioned.

    multivariate analysis to determine the correlation between physical activity and sperm parameters




Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years to 35 Years   (Adult)
Sexes Eligible for Study:   Male
Accepts Healthy Volunteers:   Yes
Sampling Method:   Probability Sample
Study Population
Candidates for sperm donors in the donation program which aims clinic It is performed in 432 cases. For that, our study addresses a population previously selected either by physical activity or by semen quality
Criteria

Inclusion Criteria:

  • Appear as sperm donor
  • Age between 18-35 years
  • First sperm donation
  • Sexual abstinence 3-5 days
  • Having signed informed consent

Exclusion Criteria:

-


Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02683057


Contacts
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Contact: Roberto Matorras +34 944806020 joseroberto.matorrasweinig@osakidetza.net
Contact: Fernando Quintana +34 944806020 ext 20504 fernando.quintana@ivi.es

Locations
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Spain
IVI Bilbao Recruiting
Leioa, Vizcaya, Spain, 48011
Contact: Roberto Matorras         
Contact: Fernando Quintana         
Sponsors and Collaborators
IVI Bilbao
Instituto Valenciano de Infertilidad, IVI VALENCIA
Investigators
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Principal Investigator: Roberto Matorras IVI Bilbao
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Responsible Party: IVI Bilbao
ClinicalTrials.gov Identifier: NCT02683057    
Other Study ID Numbers: 1411-BIO-080-RM
First Posted: February 17, 2016    Key Record Dates
Last Update Posted: February 12, 2020
Last Verified: February 2020