Working…
COVID-19 is an emerging, rapidly evolving situation.
Get the latest public health information from CDC: https://www.coronavirus.gov.

Get the latest research information from NIH: https://www.nih.gov/coronavirus.
ClinicalTrials.gov
ClinicalTrials.gov Menu

Rehabilitating Unilateral Neglect Using Spatial Working Memory Training

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
 
ClinicalTrials.gov Identifier: NCT02608190
Recruitment Status : Completed
First Posted : November 18, 2015
Last Update Posted : July 29, 2019
Sponsor:
Information provided by (Responsible Party):
James Danckert, University of Waterloo

Brief Summary:

Purpose: Stroke is a common cause of death and disability in Canada. Injury to the right hemisphere of the brain and the parietal cortex in particular, is common and results in a disorder known as 'neglect' in 40% to 95% of patients. These patients fail to attend to or respond to events occurring in left space; the disorder is devastating for the patient and their caregivers with the patient becoming dependent on assistance for most activities of daily life (ADLs).

The project will implement two visual working memory (VWM) training programs to explore the influence of VWM training on neglect symptoms as well as activities of daily life.

Hypothesis: It is hypothesised that SWM training protocols will lead to improvements of neglect symptoms as well as improvement in ADLs.

The project will develop a novel rehabilitation strategy for treating the neglect syndrome.

Evidence from research in healthy participants employing video games to improve cognition along with research using working memory training protocols showing a broad range of benefits accruing to both trained and untrained tasks, suggests that the investigators approach has great potential to improve the core deficits of the neglect syndrome. Thus, WM training represents a promising avenue for rehabilitating neglect patients who demonstrate core deficits in both spatial attention and VWM to be highly interrelated functions.


Condition or disease Intervention/treatment Phase
Hemispatial Neglect Behavioral: Working memory training Not Applicable

Show Show detailed description

Layout table for study information
Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 20 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Triple (Participant, Care Provider, Investigator)
Primary Purpose: Treatment
Official Title: Using Working Memory Training to Rehabilitate Unilateral Visual Neglect
Actual Study Start Date : November 2015
Actual Primary Completion Date : July 2019
Actual Study Completion Date : July 2019

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Memory

Arm Intervention/treatment
Experimental: Active training
Patients will undergo active working memory training (see description of protocol).
Behavioral: Working memory training
See protocol

Active Comparator: Passive training
Patients will undergo passive working memory training (see description of protocol).
Behavioral: Working memory training
See protocol




Primary Outcome Measures :
  1. Improvement on behavioural tests [ Time Frame: Measured at time zero (after intervention), 2 and 4 weeks post and 3 months post intervention. ]
    Performance on behavioural tests

  2. Improvement on self-report measures [ Time Frame: Measured at time zero (after intervention), 2 and 4 weeks post and 3 months post intervention. ]
    Changes to self-reported function in activities of daily living



Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.


Layout table for eligibility information
Ages Eligible for Study:   18 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • stroke presence of neglect symptoms

Exclusion Criteria:

  • any other neurological or psychiatric syndrome
  • any incapacity to perform the tasks

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02608190


Locations
Layout table for location information
Canada, Ontario
University of Waterloo
Waterloo, Ontario, Canada, N2L 3G1
Sponsors and Collaborators
University of Waterloo
Investigators
Layout table for investigator information
Principal Investigator: James Danckert, PhD University of Waterloo

Layout table for additonal information
Responsible Party: James Danckert, Professor, University of Waterloo
ClinicalTrials.gov Identifier: NCT02608190    
Other Study ID Numbers: Danckert
First Posted: November 18, 2015    Key Record Dates
Last Update Posted: July 29, 2019
Last Verified: July 2019
Additional relevant MeSH terms:
Layout table for MeSH terms
Perceptual Disorders
Neurobehavioral Manifestations
Neurologic Manifestations
Nervous System Diseases
Signs and Symptoms