Working…
COVID-19 is an emerging, rapidly evolving situation.
Get the latest public health information from CDC: https://www.coronavirus.gov.

Get the latest research information from NIH: https://www.nih.gov/coronavirus.
ClinicalTrials.gov
ClinicalTrials.gov Menu

Neuropsycholgy and Neuroimaging in Transient Global Amnesia (2NIA)

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
 
ClinicalTrials.gov Identifier: NCT02562560
Recruitment Status : Terminated
First Posted : September 29, 2015
Last Update Posted : November 3, 2015
Sponsor:
Information provided by (Responsible Party):
University Hospital, Caen

Brief Summary:
The purpose of this study is to establish a diagnosis in transient global amnesia (TGA) in assessing three episodic memory's abilities (mental simulation throught the future, and the past, the learning of personnal actions i-e the enactment effect). Secondary goal is to describe the neuronal substrates associated to the alteration of theses abilites in TGA.

Condition or disease Intervention/treatment Phase
Transient Global Amnesia (TGA) Behavioral: Neuropsychological tests Device: Cerebral imaging (MRI, PET-FDG) Not Applicable

Layout table for study information
Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 60 participants
Primary Purpose: Diagnostic
Official Title: Neuropsycholgy and Neuroimaging in Transient Global Amnesia
Study Start Date : September 2008
Actual Primary Completion Date : July 2015

Resource links provided by the National Library of Medicine


Arm Intervention/treatment
Experimental: TGA Behavioral: Neuropsychological tests
Device: Cerebral imaging (MRI, PET-FDG)
Experimental: Controls Behavioral: Neuropsychological tests
Device: Cerebral imaging (MRI, PET-FDG)



Primary Outcome Measures :
  1. Episodic memory scores [ Time Frame: 3 years ]


Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.


Layout table for eligibility information
Ages Eligible for Study:   30 Years to 90 Years   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • All the participants

    • Minimum of 7 years of education
    • French native speaker
  • Healthy subjects : Non pathological Dementia rating scale score
  • Patients : Clinical diagnosis of TGA according to Hodges and Warlow's criterion

Exclusion Criteria:

  • Chronic neurological disease
  • Encephalitis
  • Endocrinal disease
  • Hepatic disease
  • Case history of head injury with loss of consciousness of more than one hour
  • Case history of stroke
  • Case history of cancer during the five last years except squamous cell carcinomas
  • Alcoholism or drug addiction
  • Major psychiatric disorders according the Diagnostic and Statistical Manual of -Mental Disorders

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02562560


Sponsors and Collaborators
University Hospital, Caen
Investigators
Layout table for investigator information
Principal Investigator: Fausto Viader, PUPH University Hospital, Caen
Layout table for additonal information
Responsible Party: University Hospital, Caen
ClinicalTrials.gov Identifier: NCT02562560    
Other Study ID Numbers: 2007-A00910-53
First Posted: September 29, 2015    Key Record Dates
Last Update Posted: November 3, 2015
Last Verified: November 2015
Additional relevant MeSH terms:
Layout table for MeSH terms
Amnesia
Amnesia, Transient Global
Memory Disorders
Neurobehavioral Manifestations
Neurologic Manifestations
Nervous System Diseases
Signs and Symptoms
Neurocognitive Disorders
Mental Disorders
Brain Diseases
Central Nervous System Diseases