Effectiveness of Diclofenac and Its Association to Codeine After Lower Third Molar Extraction.
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|ClinicalTrials.gov Identifier: NCT02547896|
Recruitment Status : Completed
First Posted : September 11, 2015
Last Update Posted : September 11, 2015
|Condition or disease||Intervention/treatment||Phase|
|Impacted Third Molar Tooth||Drug: Codeine + Diclofenac Drug: Diclofenac||Phase 4|
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||50 participants|
|Intervention Model:||Crossover Assignment|
|Masking:||Double (Participant, Investigator)|
|Official Title:||Effectiveness of Non-steroidal Anti-inflammatory Diclofenac and Its Association to the Opioid Codeine for Pain, Swelling and Trismus in the Bilateral Mandibular Third Molar Extraction With a High Degree of Difficulty Model.|
|Study Start Date :||September 2014|
|Actual Primary Completion Date :||June 2015|
|Actual Study Completion Date :||September 2015|
Experimental: Pain control using codeine + diclofenac
Fifty healthy volunteers underwent removal of symmetrically positioned lower third molars, receiving for pain relief after the procedure 50mg of codeine + 50mg of diclofenac
Drug: Codeine + Diclofenac
The patients will receive codeine and diclofenac as pain relief medicine after the surgery
Experimental: Pain control using diclofenac
Fifty healthy volunteers underwent removal of symmetrically positioned lower third molars, receiving for pain relief after the procedure 50mg of diclofenac
The patients will receive only diclofenac
- Higher pain control after lower third molar surgeries with codeine + diclofenac [ Time Frame: Seven days after surgery ]Reducing pain is measured by visual analogue scale. It is expected that the visual analogue scale (100 mm) presents lower values in patients that underwent surgeries and received the association of codeine + diclofenac compared to whose received only diclofenac. Evaluated periods were 0, 15, 30, 45 min, 1, 2, 3, 4, 5, 6, 8, 12, 16, 24, 48, 72 and 96 hours.
- Adverse effects [ Time Frame: Seven days after surgery ]Increased reporting of adverse effects during the postoperative period in patients that received codeine + diclofenac assessed by the information contained in the medical records of the patient.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02547896
|Study Chair:||Paulo Z Goncalves, DDS||Bauru School of Dentistry - University of Sao Paulo - USP|