Vestibular Function After Chemoradiotherapy for Nasopharyngeal Carcinoma
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|ClinicalTrials.gov Identifier: NCT02505672|
Recruitment Status : Unknown
Verified April 2016 by yotam shkedy, Rabin Medical Center.
Recruitment status was: Not yet recruiting
First Posted : July 22, 2015
Last Update Posted : April 19, 2016
Nasopharyngeal carcinoma (NPC) is usually treated with chemoradiotherapy. While the effects of this treatment on cochlear function is well characterized, its effect on vestibular function is not well studied.
In this study the investigators will study the vestibular function of 50 patients undergoing chemoradiotherapy for NPC both before and after treatment in order to better define its effects. All patients will undergo a validated questionnaire (dizziness handicap index), posturography, audiometry and vestibular-evoked myogenic potentials.
|Condition or disease||Intervention/treatment|
|Nasopharyngeal Carcinoma||Radiation: Chemoradiotherapy for nasopharyngeal carcinoma|
|Study Type :||Observational|
|Estimated Enrollment :||50 participants|
|Official Title:||Vestibular Function After Chemoradiotherapy for Nasopharyngeal Carcinoma|
|Study Start Date :||August 2016|
|Estimated Primary Completion Date :||December 2016|
Patients older than 18 who are planned to undergo chemoradiotherapy for nasopharyngeal carcinoma.
Radiation: Chemoradiotherapy for nasopharyngeal carcinoma
Note that this is standard care for NPC and patients are not assigned to different intervention groups. All patients in the study will receive the same treatment (chemoradiotherapy) and will be observed for changes in vestibular function.
- Subjective dizziness and vestibular dysfunction using the dizziness handicap index [ Time Frame: 6 months after completion of treatment ]
- Hearing level using standard audiometry [ Time Frame: 6 months after completion of treatment ]
- Objective vestibular function using posturography [ Time Frame: 6 months after completion of treatment ]
- Vestibular saccular function using vestibular-evoked myogenic potentials [ Time Frame: 6 months after completion of treatment ]
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02505672
|Contact: Yotam Shkedy, MDfirstname.lastname@example.org|
|Department of Otolaryngology, Rabin Medical Center||Not yet recruiting|
|Petach Tikva, Israel|
|Contact: Yotam Shkedy, MD +972-3-9376458 email@example.com|
|Principal Investigator: Yotam Shkedy, MD|
|Sub-Investigator: Aaron Popovtzer, MD|