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Oxygen Desaturation During Hemodialysis

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ClinicalTrials.gov Identifier: NCT02501044
Recruitment Status : Completed
First Posted : July 17, 2015
Last Update Posted : July 17, 2015
Sponsor:
Information provided by (Responsible Party):
Renal Research Institute

Brief Summary:

Hemodialysis patients may experience drops in blood oxygen saturation during the hemodialysis treatment, which may lead to hypoxia in the tissues.

The investigators hypothesize that:

  1. The cumulative number, severity, or other characteristics of such deoxygenation episodes may be a predictor of adverse outcomes in hemodialysis patients.
  2. There may be demographic, anthropometric, clinical, treatment prescription, lab analytical, and other parameters that correlate with the number and severity of deoxygenation episodes and, therefore, may be used for risk stratification. Further, some of these parameters may be modifiable.

Condition or disease
Renal Disease Hypoxia

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Study Type : Observational
Actual Enrollment : 5500 participants
Observational Model: Cohort
Time Perspective: Retrospective
Official Title: Oxygen Desaturation During Hemodialysis: Clinical Correlates and Association With Adverse Outcomes
Study Start Date : January 2012
Actual Primary Completion Date : January 2015
Actual Study Completion Date : January 2015

Resource links provided by the National Library of Medicine


Group/Cohort
Hemodialysis Patients



Primary Outcome Measures :
  1. Cumulative number of deoxygenation episodes [ Time Frame: Up to 36 months ]
    Crit-Line III monitor recordings (which contain oxygen saturation data) will be extracted from the RRI database and the cumulative number of deoxygenation episodes will be analyzed.



Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Renal Research Institute hemodialysis patients
Criteria

Inclusion Criteria:

  • Hemodialysis patient

Exclusion Criteria:

-


Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02501044


Locations
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United States, New York
Renal Research Institute
New York, New York, United States, 10065
Sponsors and Collaborators
Renal Research Institute
Investigators
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Principal Investigator: Peter Kotanko, MD Renal Research Institute
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Responsible Party: Renal Research Institute
ClinicalTrials.gov Identifier: NCT02501044    
Other Study ID Numbers: 14-446
First Posted: July 17, 2015    Key Record Dates
Last Update Posted: July 17, 2015
Last Verified: July 2015
Additional relevant MeSH terms:
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Hypoxia
Signs and Symptoms, Respiratory
Signs and Symptoms