A Comparison Study Between Ketamine Versus Tramadol for Pain Management After Major Upper Abdominal Surgery
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.|
|ClinicalTrials.gov Identifier: NCT02499341|
Recruitment Status : Completed
First Posted : July 16, 2015
Last Update Posted : July 16, 2015
|Condition or disease||Intervention/treatment||Phase|
|Postoperative Pain||Drug: Tramadol Drug: Ketamine||Not Applicable|
Show Detailed Description
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||42 participants|
|Intervention Model:||Parallel Assignment|
|Official Title:||Comparison Between Ketamine and Tramadol for Pain Management After Major Upper Abdominal Surgery|
|Study Start Date :||July 2011|
|Actual Primary Completion Date :||July 2014|
|Actual Study Completion Date :||July 2014|
Active Comparator: Tramadol
Intraoperative administration of a bolus dose of tramadol and continuous intravenous infusion of tramadol for up to 48 h postoperatively.
Tramadol administered intravenously (1mg/kg) thirty minutes before the expected end of surgery, followed by a continuous infusion of tramadol (0.2mg•kg-¹•h-¹) for up to 48 h after major upper abdominal surgery, in patients receiving PCA morphine postoperatively at a bolus dose of 1 mg with a lockout period of 8 minutes.
Other Name: Tramal
Active Comparator: Ketamine
Intraoperative administration of a bolus dose of ketamine and continuous intravenous infusion of ketamine for up to 48 h postoperatively.
Ketamine administered intravenously (0.5mg/kg) thirty minutes before the expected end of surgery, followed by a continuous infusion of ketamine (0.12mg•kg-¹•h-¹) for up to 48 h after major upper abdominal surgery, in patients receiving PCA morphine postoperatively at a bolus dose of 1 mg with a lockout period of 8 minutes.
Other Name: Ketalar
- Measurement of morphine consumption expressed as milligrams postoperatively in abdominal surgery. [ Time Frame: 48 hours postoperatively ]
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02499341
|2nd Department of Anesthesiology, Attikon University Hospital|
|Athens, Attiki, Greece, 12462|
|Principal Investigator:||Paraskevi Matsota, MD, PhD||Attikon University Hospital, Athens, Greece|