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Effects of Hydrocortisone on Social Cognition and Memory (CORT-COG)

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ClinicalTrials.gov Identifier: NCT02478021
Recruitment Status : Completed
First Posted : June 23, 2015
Last Update Posted : June 23, 2015
Sponsor:
Information provided by (Responsible Party):
Katja Wingenfeld, Charite University, Berlin, Germany

Brief Summary:
The effects of hydrocortisone on cognition will be investigated.

Condition or disease Intervention/treatment Phase
Individuality Other: Hydrocortisone Not Applicable

Detailed Description:
80 healthy young individuals (40 females and 40 male) will be recruited an randomized to either placebo or 10 mg hydrocortisone before testing. Tasks will on emotion recognition, memory and cognitive flexibilty will be conducted.

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Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 80 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double (Participant, Investigator)
Primary Purpose: Basic Science
Official Title: Effekte Von Hydrocortison Auf Soziale Kognition Und Gedächtnis Unter Berücksichtigung Von Geschlechtereffekten
Study Start Date : September 2014
Actual Primary Completion Date : May 2015
Actual Study Completion Date : May 2015


Arm Intervention/treatment
Experimental: Hydrocortisone
10 mg hydrocortisone
Other: Hydrocortisone
Effects of hydrocortisone compared to placebo on cognition

Placebo Comparator: Placebo
1 pill Placebo
Other: Hydrocortisone
Effects of hydrocortisone compared to placebo on cognition




Primary Outcome Measures :
  1. social cognition [ Time Frame: 25 min ]
    computer based test: Multifaceted Empaty test


Secondary Outcome Measures :
  1. memory [ Time Frame: 25 min ]
    autobiographic memory test (AMT)

  2. cognitive flexibilty [ Time Frame: 10 min ]
    computer based test: task switch



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Ages Eligible for Study:   18 Years to 30 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • age 18 - 30
  • medication free

Exclusion Criteria:

  • any medication
  • severe ilness

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02478021


Locations
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Germany
Charite University
Berlin, Germany
Sponsors and Collaborators
Charite University, Berlin, Germany
Investigators
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Principal Investigator: Katja Wingenfeld Charite University

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Responsible Party: Katja Wingenfeld, PhD, Head: Clinical Psycology, Charite University, Berlin, Germany
ClinicalTrials.gov Identifier: NCT02478021     History of Changes
Other Study ID Numbers: WI-CO-1
First Posted: June 23, 2015    Key Record Dates
Last Update Posted: June 23, 2015
Last Verified: June 2015
Keywords provided by Katja Wingenfeld, Charite University, Berlin, Germany:
effects of cortisol on cognition
Additional relevant MeSH terms:
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Hydrocortisone
Hydrocortisone 17-butyrate 21-propionate
Hydrocortisone acetate
Hydrocortisone hemisuccinate
Anti-Inflammatory Agents