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Breath-hold Cardiac Hybrid SPECT/CCTA

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
 
ClinicalTrials.gov Identifier: NCT02469051
Recruitment Status : Completed
First Posted : June 11, 2015
Last Update Posted : May 11, 2016
Sponsor:
Information provided by (Responsible Party):
University of Zurich

Brief Summary:
This study aims at combining inspiration breath-hold myocardial perfusion SPECT with coronary CT angiography.

Condition or disease Intervention/treatment Phase
Coronary Artery Disease Device: Breathhold SPECT-MPI Device: Standard freebreathing SPECT-MPI Device: Coronary CT angiography Not Applicable

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Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 50 participants
Allocation: N/A
Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Diagnostic
Official Title: Usefulness of Breath-hold Triggered SPECT-MPI in Cardiac Hybrid SPECT/CCTA Imaging
Study Start Date : May 2015
Actual Primary Completion Date : May 2016
Actual Study Completion Date : May 2016

Arm Intervention/treatment
Breathhold SPECT-MPI vs. standard freebreathing SPECT-MPI Device: Breathhold SPECT-MPI
Respiratory triggered SPECT myocardial perfusion imaging

Device: Standard freebreathing SPECT-MPI
Clinically indicated, standard non-respiratory triggered SPECT myocardial perfusion imaging

Device: Coronary CT angiography
Clinically indicated coronary CT angiography serving as standard of reference
Other Name: CCTA




Primary Outcome Measures :
  1. Image quality as visually assessed on a Likert scale [ Time Frame: 1 day ]
  2. Number of image artefacts [ Time Frame: 1 day ]


Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Referral for cardiac hybrid SPECT/CCTA
  • Male and female subjects 18 years of age or older
  • Written informed consent by the participant after information about the project

Exclusion Criteria:

  • Contraindications for coronary CT angiography (including renal failure with a GFR <30ml/min/1.73m2, allergies to iodinated contrast agents)
  • Pregnancy or breast-feeding
  • Previous coronary revascularisation
  • Inability to follow the examination procedure (e.g. due to language barriers, severe mental disease etc

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02469051


Locations
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Switzerland
Department of Nuclear Medicine, University Hospital Zurich
Zurich, Switzerland, 8091
Sponsors and Collaborators
University of Zurich
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Responsible Party: University of Zurich
ClinicalTrials.gov Identifier: NCT02469051    
Other Study ID Numbers: USZ-2015-0098
First Posted: June 11, 2015    Key Record Dates
Last Update Posted: May 11, 2016
Last Verified: May 2016
Additional relevant MeSH terms:
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Coronary Artery Disease
Coronary Disease
Myocardial Ischemia
Heart Diseases
Cardiovascular Diseases
Arteriosclerosis
Arterial Occlusive Diseases
Vascular Diseases