Vicente Ferrer HIV Cohort Study (VFHCS)
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|ClinicalTrials.gov Identifier: NCT02454569|
Recruitment Status : Recruiting
First Posted : May 27, 2015
Last Update Posted : April 20, 2018
|Condition or disease|
|HIV Tuberculosis Cryptococcosis Opportunistic Infections Noncommunicable Diseases|
Andhra Pradesh is the state with highest burden of HIV in India. Anantapur is a district situated in the South border of Andhra Pradesh with 72% rural population and adult literacy rate of 74.1% in men and 54.3% in women. In Anantapur, the HIV epidemic is largely driven by heterosexual transmission and it is characterized by poor socioeconomic conditions and high levels of illiteracy.
Rural Development Trust (RDT) is a nongovernmental organization, which provides medical care to people living with HIV free of charge, including medicines, consultation and admission charges. In Bathalapalli Hospital, outpatient clinics and 71 beds are allocated exclusively for HIV or tuberculosis infected patients.
The Vicente Ferrer HIV Cohort Study (VFHCS) is a prospective open cohort study of all HIV infected patients who have attended Bathalapalli RDT Hospital. Routine clinical data from patients are collected prospectively since September 2009 and entered in a SQL-server database using C# as front end. Details of route of transmission, HIV associated risk factors and socio-demographic data are collected at enrolment. Data collected include medical treatment (antiretroviral treatment and other medications), laboratory investigations (haemogram, renal function tests, liver function tests, CD4 lymphocyte count, bacterial infections), and standardized diagnoses.
The objective of the VFHCS is to describe social and medical aspects related to HIV in the investigators setting, including:
- Epidemiology: trends in HIV incidence, transmission mechanisms, socioeconomic risk factors associated with HIV.
- Incidence and prevalence of opportunistic infections, especially tuberculosis and cryptococcosis.
- Life expectancy and factors associated with mortality
- Describe the retention across the continuum of care and investigate factors associated with loss to follow-up.
- Toxicity and effectiveness of antiretroviral therapy.
- Effectiveness of programmes to prevent mother to child transmission.
- Incidence and prevalence of non-communicable diseases such as cancer or cardiovascular diseases.
|Study Type :||Observational [Patient Registry]|
|Estimated Enrollment :||30000 participants|
|Target Follow-Up Duration:||30 Years|
|Official Title:||Vicente Ferrer HIV Cohort Study|
|Study Start Date :||September 2009|
|Estimated Primary Completion Date :||September 2039|
|Estimated Study Completion Date :||January 2040|
- Mortality [ Time Frame: Time to event methods will be used. Participants will be followed from HIV diagnosis until death, assessed up to 30 years ]Survival since diagnosis of HIV infection
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02454569
|Contact: Gerardo Alvarez-Uriafirstname.lastname@example.org|
|Battalapalli, AP, India, 515661|
|Contact: Gerardo Alvarez Uria, MD PhD email@example.com|
|Principal Investigator: Gerardo Alvarez-Uria|
|Principal Investigator:||Gerardo Alvarez-Uria||Rural Development Trust|