Review of Human Herpes Viruses in Burns
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|ClinicalTrials.gov Identifier: NCT02452229|
Recruitment Status : Completed
First Posted : May 22, 2015
Last Update Posted : May 22, 2015
|Condition or disease||Intervention/treatment|
|Human Herpes Virus Herpes Simplex Virus Varicella-zoster Virus Chickenpox Cytomegalovirus Burns||Other: Review of the Literature for Human Herpes Virus infections|
This systematic review was created according the PRIMSA (preferred reporting items for systematic reviews and meta-analyses) guidelines and checklist.
We performed an review of the medical literature to identify all studies that contain HSV, CMV and VZV infections in burns.Therefore, systematic review of the Medline database by using PubMed and Ovid interface was conducted. Also the Web of Science interface was used for systematic literature search.
On the PubMed interface, we used the following search terms: ("HSV"[All Fields] OR "herpes"[All Fields] OR "CMV"[All Fields] OR "cytomegalovirus"[All Fields] OR "VZV"[All Fields] OR "varicella-zoster"[All Fields]) AND ("burns"[MeSH Terms] OR "burns"[All Fields] OR "burn"[All Fields] OR "thermal trauma"[All Fields]). For Ovid we used: exp Burns/ AND (exp Herpes Zoster/ or exp Encephalitis, Herpes Simplex/ or exp Herpes Simplex/ or exp Herpes Simples Virus Vaccines/), exp Burns/ AND (exp Cytomegalovirus/ or exp Cytomegalovirus Infections/), exp Burns/ AND (exp Chickenpox/ or Herpesvirus 3. Human/ or exp Herpes Zoster/). And for Web of Science we used: (TS=(HSV OR herpes OR CMV OR cytomegalovirus OR VZV OR varicella-zoster) AND TS=(burn OR burns OR thermal trauma)) AND LANGUAGE: (English) AND DOCUMENT TYPES: (Article); Timespan: All years; Indexes: SCI-EXPANDED, SSCI, A&HCI, CPCI-S.
|Study Type :||Observational|
|Actual Enrollment :||10267 participants|
|Official Title:||Human Herpes Viruses in Burn Victims: A Systematic Review|
|Study Start Date :||March 2015|
|Actual Primary Completion Date :||May 2015|
The included patient are burn victims who sustained a burn of at least 1 % total body surface are (TBSA); with no restriction on age.
Other: Review of the Literature for Human Herpes Virus infections
Review of the Medline database (PubMed and Ovid interface) for human herpes virus infections in burns as well as Web of Science interface.
PRIMSA (preferred reporting items for systematic reviews and meta-analyses) guidelines and checklist were used.
- Prevalence of Human Herpes Virus (HHV) Infections [ Time Frame: Participants will be followed for the duration of hospital stay, an expected average of 3 months. ]HHV include the herpes simplex virus type 1 (HSV-1), herpes simplex virus type 2 (HSV-2), varicella zoster virus (VZV), cytomegalovirus (CMV), Epstein-Barr viruses (EBV) and human herpes virus 6 to 8
- Treatment of Human Herpes Virus (HHV) Infections [ Time Frame: Participants will be followed for the duration of hospital stay, an expected average of 3 months. ]
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02452229
|Study Chair:||David N Herndon, MD, FACS||Department of Surgery, University of Texas Medical Branch and Shriners Hospitals for Children, Galveston, Texas, USA|