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Trial record 38 of 82 for:    acne AND Acne Scars

Clinical Effect of Platelet Rich Plasma Combined With Laser on Scar

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ClinicalTrials.gov Identifier: NCT02396290
Recruitment Status : Completed
First Posted : March 24, 2015
Last Update Posted : March 24, 2015
Sponsor:
Information provided by (Responsible Party):
Seoul National University Hospital

Brief Summary:
Investigation of Clinical Effect of Platelet Rich Plasma Combined With Laser on Acne Scar

Condition or disease Intervention/treatment Phase
Acne Scar Procedure: fractional carbon dioxide laser with platelet rich plasma Procedure: fractional carbon dioxide laser with NS Not Applicable

Detailed Description:
Platelet Rich Plasma may relieve the adverse effect of laser treatment. and it can be expected to improve acne treatment result.

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Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 29 participants
Allocation: Randomized
Intervention Model: Single Group Assignment
Masking: Double (Participant, Outcomes Assessor)
Primary Purpose: Treatment
Official Title: Clinical Study on Efficacy and Safety of Platelet Rich Plasma Combined With Laser for Scar Treatment
Study Start Date : March 2013
Actual Primary Completion Date : September 2013
Actual Study Completion Date : September 2013

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Acne Scars

Arm Intervention/treatment
Experimental: fractional CO2 laser with PRP
fractional carbon dioxide laser followed by intradermal injection of platelet rich plasma
Procedure: fractional carbon dioxide laser with platelet rich plasma
fractional carbon dioxide laser followed by platelet rich plasma injection
Other Name: COFRAX with autologous PRP

Active Comparator: fractional CO2 laser with NS
fractional carbon dioxide laser followed by intradermal injection of NS
Procedure: fractional carbon dioxide laser with NS
fractional carbon dioxide laser followed by normal saline injection
Other Name: COFRAX with normal saline




Primary Outcome Measures :
  1. Global assessment of acne scar [ Time Frame: 12 weeks ]
    5-point grading of acne scar


Secondary Outcome Measures :
  1. ECCA (échelle d'évaluation clinique des cicatrices d'acné) [ Time Frame: 12 weeks ]
    quantitative analysis of acne scar

  2. adverse effect assessment [ Time Frame: 12 weeks ]
    adverse effect assessment - erythema index, Epithelization Scale (0-12 point)



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Ages Eligible for Study:   19 Years to 40 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • moderate to severe acne scar

Exclusion Criteria:

  • taken procedures for acne scar within 6 months
  • underlying diabetes mellitus, keloid, or malignancy

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02396290


Locations
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Korea, Republic of
Department of Dermatology, Seoul National University College of Medicine
Seoul, Korea, Republic of, 110-744
Sponsors and Collaborators
Seoul National University Hospital
Investigators
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Study Chair: Dae Hun Suh, PhD Department of Dermatology, Seoul National University College of Medicine
Principal Investigator: Seonguk Min, Msc Department of Dermatology, Seoul National University College of Medicine

Publications:
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Responsible Party: Seoul National University Hospital
ClinicalTrials.gov Identifier: NCT02396290     History of Changes
Other Study ID Numbers: 2012-0998
First Posted: March 24, 2015    Key Record Dates
Last Update Posted: March 24, 2015
Last Verified: July 2013

Keywords provided by Seoul National University Hospital:
acne scar
fractional carbon dioxide laser
platelet rich plasma