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Chronic Pain Dynamic Psychophysical Tests and Genetic Screening

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ClinicalTrials.gov Identifier: NCT02373696
Recruitment Status : Completed
First Posted : February 27, 2015
Last Update Posted : September 4, 2015
Sponsor:
Information provided by (Responsible Party):
KK Women's and Children's Hospital

Brief Summary:
Incidence and risk factors for persistent post surgical pain after Caesarean section are investigated. Demographic, psychophysical testing and genetic screening factors are performed in the perioperative period. Phone survey is performed to investigate the incidence of persistent post surgical pain after Caesarean section.

Condition or disease
Pain

Detailed Description:
Persistent post surgical pain after Caesarean section may lead to functional limitation and pain during activities of daily living. Demographic factors, psychophysical factors (mechanical temporal summation, diffuse noxious inhibitory control, state trait anxiety inventory) and genetic screening are used to predict the association with persistent post surgical pain. Phone survey follow up is performed to investigate the incidence of persistent post surgical pain and functional limitations due to pain experienced.

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Study Type : Observational
Actual Enrollment : 178 participants
Observational Model: Cohort
Time Perspective: Prospective
Official Title: Prediction of Chronic Pain in the Asian Population- Comprehensive Programme Encompassing Dynamic Psychophysical Tests and Genetic Screening to Determine and Prevent Persistent Post-caesarean Pain
Study Start Date : April 2010
Actual Primary Completion Date : January 2015
Actual Study Completion Date : January 2015

Resource links provided by the National Library of Medicine





Primary Outcome Measures :
  1. Persistent Postsurgical Pain [ Time Frame: 12 weeks ]
    Pain experienced in the lower abdominal region and surgical area after Caesarean section


Biospecimen Retention:   Samples With DNA
Blood sampling


Information from the National Library of Medicine

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Ages Eligible for Study:   21 Years to 50 Years   (Adult)
Sexes Eligible for Study:   Female
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Women undergoing spinal anaesthesia for Caesarean section
Criteria

Inclusion Criteria:

  • Women undergoing spinal anaesthesia for Caesarean section

Exclusion Criteria:

  • Failed spinal anaesthesia, Unable to perform psychophysical testing.

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02373696


Locations
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Singapore
KK Women's and Children's Hospital
Singapore, Singapore, 229899
Sponsors and Collaborators
KK Women's and Children's Hospital
Investigators
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Principal Investigator: Ban L Sng, FANZCA KK Women's and Children's Hospital
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Responsible Party: KK Women's and Children's Hospital
ClinicalTrials.gov Identifier: NCT02373696    
Other Study ID Numbers: 2010/160/D
First Posted: February 27, 2015    Key Record Dates
Last Update Posted: September 4, 2015
Last Verified: September 2015
Keywords provided by KK Women's and Children's Hospital:
Pain
Caesarean section
Additional relevant MeSH terms:
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Chronic Pain
Pain
Neurologic Manifestations