Assessing the Effectiveness of a Water Filter Technology as an Arsenic Mitigation Strategy in West Bengal
|ClinicalTrials.gov Identifier: NCT02372851|
Recruitment Status : Completed
First Posted : February 26, 2015
Last Update Posted : September 12, 2016
|Condition or disease||Intervention/treatment||Phase|
|Total Urinary Arsenic Total Arsenic in Water Diarrhoeal Disease||Device: Pureit As+ Filter||Not Applicable|
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||362 participants|
|Intervention Model:||Parallel Assignment|
|Masking:||None (Open Label)|
|Official Title:||Assessing the Effectiveness of a Point-of-use Water Filter Technology as an Arsenic Mitigation Strategy in West Bengal|
|Study Start Date :||January 2015|
|Actual Primary Completion Date :||July 2015|
|Actual Study Completion Date :||July 2015|
Active Comparator: Pureit As+ Filter
Each household will receive one water filter and a replacement battery for free during distribution. The intervention will be distributed door-to-door by the implementation team. Households will be trained on use and maintenance of the device according to the manufacturer's instructions. Households will be advised to drink exclusively from the water filter and to carry water with them if attending school or work. Households will also be advised to clean and cook their rice with filtered water only.
Device: Pureit As+ Filter
The Pureit As+ water filter has been developed to effectively remove arsenic (both arsenite and arsenate) from over 300 µg/L to less than 10 µg/L in addition to removing microbial contamination (Institution of Public Health Engineers, 2011). It has an end-of-life indicator and consumables that do not re-contaminate the environment when disposed (Institution of Public Health Engineers, 2011). The technology requires no electricity, but only the replacement of the battery after 1000 L of water filtered (approximately 100 days based on a family of five drinking 2 L/day).
No Intervention: Control arm
The control arm will be advised to continue with their traditional drinking water and cooking practices. The control arm will receive the intervention at the end of the study period.
- Total urinary arsenic [ Time Frame: 4 months ]To assess the effectiveness of the Unilever Pureit As+ technology in decreasing the body burden of arsenic, measured in terms of total urinary arsenic
- Total arsenic removal in drinking water [ Time Frame: 4 months ]Median and arithmetic mean of total arsenic concentration in intervention vs. control households stored drinking water
- Total arsenic reduction in filtered water [ Time Frame: 4 months ]To assess total arsenic removal performance in drinking water of the Unilever Pureit As+ technology in the field (Mean % removal).
- Mean TTC reduction in drinking water [ Time Frame: 4 months ]Williams mean of CFU/100 mL in intervention vs. control household stored drinking water
- Self-reported use of the intervention [ Time Frame: 4 months ]To examine consistent use of Unilever Pureit As+ technology, for children <5 years and all household members
- Consistent use [ Time Frame: 4 months ]To examine consistent use of Unilever Pureit As+ technology using objective indicators of use
- Prevalence of diarrhoea among <5s [ Time Frame: 4 months ]To examine the impact of the Unilever Pureit As+ technology on reported diarrhoea among children under 5 years
- Prevalence of diarrhoea among all family members [ Time Frame: 4 months ]5) To examine the impact of the Unilever Pureit As+ technology on reported diarrhoea among all family members.
- Bacterial removal [ Time Frame: 4 months ]Mean % removal (log reduction) of TTC for intervention households
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02372851
|Gobardanga Seba Farmer's Samity (GSFS)|
|Gobardanga, North 24 Parganas, West Bengal, India|
|Principal Investigator:||Thomas Clasen, JD MSc PhD||LSHTM & Emory University|