Lactate in Cardiac Arrest
|ClinicalTrials.gov Identifier: NCT02352350|
Recruitment Status : Withdrawn (Measurement devices unavailable at this time.)
First Posted : February 2, 2015
Last Update Posted : October 24, 2017
|Condition or disease||Intervention/treatment|
|Cardiac Arrest Neurological Injury||Other: Blood Lactate Levels Other: Neurological Outcomes|
|Study Type :||Observational|
|Actual Enrollment :||0 participants|
|Official Title:||The Predictive Value of Prehospital Blood Lactate Measurement Following Out of Hospital Cardiac Arrest (OHCA) and Return of Spontaneous Circulation (ROSC).|
|Estimated Study Start Date :||September 2017|
|Estimated Primary Completion Date :||November 2018|
|Estimated Study Completion Date :||January 2019|
Cardiac Arrest Patients
All adult patients with non traumatic cardiac arrest in Alachua County Florida will have blood lactate levels taken and neurological outcomes performed based on the Cerebral Performance Categories (CPC) Scale
Other: Blood Lactate Levels
Blood lactate levels will be performed on all participants.
Other: Neurological Outcomes
Neurological outcomes will be performed on all participants based on the Cerebral Performance Categories (CPC) Scale.
Other Name: Cerebral Performance Categories (CPC) Scale
- Blood Lactate Levels correlated with survival [ Time Frame: Changes in hour 0, approximately hour 12, approximately day 14, and 6 months ]
- Blood Lactate Levels correlated with Neurological Outcomes [ Time Frame: Changes in week 2 and 6 months ]
Overall Neurologic function will be assessed using available clinical information and Cerebral Performance Categories, a composite measure including available neurologic and clinical assessments CPC 1. Good cerebral performance: conscious, alert, able to work, might have mild neurologic or psychological deficit.
CPC 2. Moderate cerebral disability: conscious, sufficient cerebral function for independent activities of daily life. Able to work in sheltered environment.
CPC 3. Severe cerebral disability: conscious, dependent on others for daily support because of impaired brain function. Ranges from ambulatory state to severe dementia or paralysis.
CPC 4. Coma or vegetative state: any degree of coma without the presence of all brain death criteria. Unawareness, even if appears awake (vegetative state) without interaction with environment; may have spontaneous eye opening and sleep/awake cycles. Cerebral unresponsiveness.
CPC 5. Brain death: apnea, areflexia, EEG silence, etc.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02352350
|Principal Investigator:||Karl Huesgen, MD||University of Florida|