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Trial record 28 of 415 for:    Gonadotrophin, Chorionic AND Choriogonadotropin Alfa

Intrauterine Injection of Human Chorionic Gonadotropin Before Embryo Transfer in Women With Previous IVF Failure

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ClinicalTrials.gov Identifier: NCT02329197
Recruitment Status : Unknown
Verified December 2014 by Ahmed Gibreel, Mansoura University.
Recruitment status was:  Recruiting
First Posted : December 31, 2014
Last Update Posted : December 31, 2014
Sponsor:
Information provided by (Responsible Party):
Ahmed Gibreel, Mansoura University

Brief Summary:
Women with history of previous IVF cycle failure will be subjected to a fresh IVF cycle. At the time they will be undergoing embryo transfer, 50 IU of human chorionic gonadotropins diluted in 0.025ml of tissue culture media will be injected intrauterine by embryo transfer catheter 10 minutes before embryo transfer procedure.

Condition or disease Intervention/treatment Phase
Infertility Invitro Fertilization Drug: Human Chorionic Gonadotropin (HCG) Phase 4

Detailed Description:
Infertile women with history of previous IVF cycle failure will be subjected top a fresh IVF cycle. Following controlled ovarian hyperstimulation, ovum pick up and at the time they will be undergoing embryo transfer, 50 IU of human chorionic gonadotropins diluted in 0.025ml of tissue culture media will be injected intrauterine by embryo transfer catheter 10 minutes before embryo transfer procedure.

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Study Type : Interventional  (Clinical Trial)
Estimated Enrollment : 380 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double (Participant, Outcomes Assessor)
Primary Purpose: Treatment
Study Start Date : October 2014
Estimated Primary Completion Date : October 2015
Estimated Study Completion Date : March 2016

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Infertility

Arm Intervention/treatment
Experimental: Group A
women undergoing IVF treatment will be subjected for intrauterine injection of 10 IU of human chorionic gonadotropin (HCG) (diluted in 0.025ml of tissue culture), 10 minutes before embryo transfer procedure.
Drug: Human Chorionic Gonadotropin (HCG)
intrauterine injection of HCG prior to embryo transfer in an IVF cycle
Other Name: u-hCG

No Intervention: Group B
women undergoing IVF treatment will embryo transfer procedure performed in the standard way without intrauterine injection of HCG.



Primary Outcome Measures :
  1. Live Birth [ Time Frame: 9 months ]


Information from the National Library of Medicine

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Ages Eligible for Study:   19 Years to 40 Years   (Adult)
Sexes Eligible for Study:   Female
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

- women with previous IVF failure undergoing fresh IVF cycle

Exclusion Criteria:

  • women with hydrosalpinges women with intrauterine lesion like submucous fibroid or polyps

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02329197


Contacts
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Contact: Ahmed Gibreel, MD 002/01004045733 ahmedfathgi@yahoo.com

Locations
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Egypt
Mansoura University Teaching Hospital Recruiting
Mansoura, Egypt, 53111
Principal Investigator: Ahmed Gibreel, MD         
Sponsors and Collaborators
Mansoura University
Investigators
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Principal Investigator: Ahmed Gibreel, MD Mansoura University

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Responsible Party: Ahmed Gibreel, Dr, Mansoura University
ClinicalTrials.gov Identifier: NCT02329197     History of Changes
Other Study ID Numbers: H005
First Posted: December 31, 2014    Key Record Dates
Last Update Posted: December 31, 2014
Last Verified: December 2014
Keywords provided by Ahmed Gibreel, Mansoura University:
Infertility
Invitro fertilization
Additional relevant MeSH terms:
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Infertility
Genital Diseases, Male
Genital Diseases, Female
Chorionic Gonadotropin
Reproductive Control Agents
Physiological Effects of Drugs