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Efficacy of Microcurrent Therapy After Eccentric Exercise

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ClinicalTrials.gov Identifier: NCT02322489
Recruitment Status : Completed
First Posted : December 23, 2014
Last Update Posted : June 9, 2015
Sponsor:
Information provided by (Responsible Party):
Christophe Demoulin, University of Liege

Brief Summary:

15 participants will be included in the present study. They will attend two groups of three sessions (i.e. sessions 1-2-3 and sessions 4-5-6) spaced by 3 months:

  • session 1 and 4 (performed a few days before the experimental session): session for participants to get familiarized with the test battery.
  • session 2 and 5: experimental session (the test battery followed by the provocative task, the test battery, the one-hour "treatment" and the test battery again).
  • session 3 and 6 (performed 2 days later): the test battery.

The test battery included flexibility, functional, pressure pain threshold tests.

The provocative task was an isokinetic eccentric task for knee flexors and extensors.

The treatment was either a microcurrent therapy or a placebo microcurrent therapy.


Condition or disease Intervention/treatment Phase
Delayed Onset Muscle Soreness Device: Microcurrent Therapy Device: Sham microcurrent therapy Not Applicable

Detailed Description:

Objective:

To study the efficacy of microcurrent to reduce DOMS (Delayed Onset Muscle Soreness) occuring after an eccentric exercise

Methods:

Experimental protocol

Participants will attend two groups of three sessions (i.e. sessions 1-2-3 and sessions 4-5-6) spaced by 3 months:

  • session 1 and 4 (performed a few days before the experimental session): session for participants to get familiarized with the test battery.
  • session 2 and 5: experimental session: the test battery followed by the provocative task, the test battery, the one-hour "treatment" (real microcurrents at one of the session and placebo microcurrents at the other one) and the test battery again.
  • session 3 and 6 (performed 2 days later): the test battery.

Before starting session 2, patients will be randomized into the microcurrent group or the placebo microcurrent group. Three months later, participants will change of group.

The Test Battery: it will be conducted by a blind (to the treatment) investigator. It will include knee flexor and extensor flexibility tests, a functional test (unilateral " counter-movement jump "), a pain to measure pain threshold of thigh muscles and an isometric maximal voluntary contraction (MVC) test of knee flexors and extensors.

The Provocative task: 40 isokinetic eccentric contractions of knee flexors and extensors.

The one-hour Treatment: with the participant lying on an examination table, several electrodes were located over the muscles involved in the provocative task. The microcurrent therapy was then started. It was stopped after 5 seconds in the "Placebo group" and after one hour in the real "Microcurrent group". The microcurrents were delivered by the machine B-E-St®.

Follow-up: in addition to the 48hours follow-up (session 3/6), participants will fill in a pain visual analogue scale each day after the session 2/5.


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Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 15 participants
Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: Double (Participant, Outcomes Assessor)
Primary Purpose: Prevention
Official Title: Efficacy of Microcurrent Therapy After Eccentric Exercise
Study Start Date : January 2015
Actual Primary Completion Date : May 2015
Actual Study Completion Date : June 2015

Arm Intervention/treatment
Sham Comparator: Sham microcurrent therapy
The participant is lying on an examination table for one hour; several electrodes are placed over the muscles involved in the provocative task. The microcurrent therapy is then started but it lasts only for 5 seconds.
Device: Sham microcurrent therapy
Several electrodes are placed over the muscles involved in the provocative task. The microcurrent therapy is then started but lasts only for five seconds.

Experimental: Microcurrent Group
The participant is lying on an examination table for one hour; several electrodes are placed over the muscles involved in the provocative task. The microcurrent therapy is then started.
Device: Microcurrent Therapy
Several electrodes are placed over the muscles involved in the provocative task. The microcurrent therapy is then started and lasts for one hour.




Primary Outcome Measures :
  1. Intensity of pain (Visual analogue scale) [ Time Frame: baseline, post-provocative task, post-treatment, 48h follow-up, following days until pain disappears ]

Secondary Outcome Measures :
  1. Flexibility of quadriceps and hamstrings muscles [ Time Frame: baseline, post-provocative task, post-treatment, 48h follow-up ]

    Flexibility of quadriceps muscle was assessed by means of the Prone Quadriceps Flexibility test.

    Flexibility of hamstrings was assessed by means of the Straight Leg Raising (SLR) test


  2. Functional test (Unilateral counter-movement jump) [ Time Frame: baseline, post-provocative task, post-treatment, 48h follow-up ]
    Unilateral counter-movement jump

  3. Pain sensibility threshold (Determined by using a dolorimeter) [ Time Frame: baseline, post-provocative task, post-treatment, 48h follow-up ]
    Determined by using a dolorimeter

  4. Isometric strength (Maximal voluntary contraction of knee flexor and extensor muscles) [ Time Frame: baseline, post-provocative task, post-treatment, 48h follow-up ]
    Maximal voluntary contraction of knee flexor and extensor muscles



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Ages Eligible for Study:   18 Years to 25 Years   (Adult)
Sexes Eligible for Study:   Male
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • Asymptomatic subjects

Exclusion Criteria:

  • practice of sports >3h per week
  • present pain in the lower limbs
  • history of thigh muscle injuries
  • recent injury (last 3 months) of the lower limbs
  • recent (last 3 months) plyometric exercises or lower limbs strengthening program.

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02322489


Locations
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Belgium
Liege University Hospital Center
Liege, Belgium, 4000
Sponsors and Collaborators
University of Liege
Investigators
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Principal Investigator: Christophe Demoulin, PhD University of Liege

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Responsible Party: Christophe Demoulin, Main investigator, University of Liege
ClinicalTrials.gov Identifier: NCT02322489     History of Changes
Other Study ID Numbers: Microcurrent
First Posted: December 23, 2014    Key Record Dates
Last Update Posted: June 9, 2015
Last Verified: June 2015

Keywords provided by Christophe Demoulin, University of Liege:
microcurent
pain
flexibility

Additional relevant MeSH terms:
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Myalgia
Muscular Diseases
Musculoskeletal Diseases
Neuromuscular Diseases
Nervous System Diseases
Musculoskeletal Pain
Pain
Neurologic Manifestations
Signs and Symptoms