Neuromuscular Control in Knee Osteoarthritis (NEKO)
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.|
|ClinicalTrials.gov Identifier: NCT02314715|
Recruitment Status : Completed
First Posted : December 11, 2014
Last Update Posted : March 3, 2015
|Condition or disease|
|Study Type :||Observational|
|Actual Enrollment :||95 participants|
|Observational Model:||Case Control|
|Official Title:||Neuromuscular Control in Knee Osteoarthritis|
|Study Start Date :||November 2013|
|Actual Primary Completion Date :||February 2015|
|Actual Study Completion Date :||February 2015|
Participants with diagnosed knee osteoarthritis
Participants without knee osteoarthritis
- Neuromuscular Control [ Time Frame: 1 day ]Neuromuscular control will be assessed through muscle co-activation index from electromyography (EMG) of the hamstrings, quadriceps and gastrocnemius. The electromechanical delay (delay between the onset of EMG and force), active proprioception and force accuracy and steadiness measure determined from submaximal isometric contractions will be used to determine neuromuscular control
- Disease Outcome [ Time Frame: 1 day ]Joint damage scored using the Boston Leeds Osteoarthritis Knee Score (BLOKS) from 1.5T MRI along with pain and function assessed from knee injury and osteoarthritis score (KOOS) and patient reported outcomes measurement information system (PROMIS) will be used to determine disease outcome.
- Determinants of knee osteoarthritis [ Time Frame: 1 day ]Muscle strength (peak force) will be assessed from maximal isometric contractions of the knee, along with passive motion and position sense proprioception as determinants of knee osteoarthritis.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02314715
|Glasgow Caledonian University|
|Glasgow, United Kingdom, G4 0BA|
|Principal Investigator:||Stephanie L Smith, MRes||Glasgow Caledonian University|