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Trial record 51 of 182 for:    ERYTHROMYCIN

Assessment of Prokinetic Effects of Erythromycin in Emergency Patients With a Full Stomach

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT02296866
Recruitment Status : Completed
First Posted : November 20, 2014
Last Update Posted : December 30, 2014
Information provided by (Responsible Party):
Lionel Bouvet, Hôpital Edouard Herriot

Brief Summary:
The aims of the study is to assess whether the intravenous infusion of 3 mg/kg erythromycin has a significant gastrokinetic effect leading to empty the stomach in less than 90 minutes in non-fasting patients undergoing emergency trauma surgery.

Condition or disease
Emergency Surgery Full Stomach

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Study Type : Observational
Actual Enrollment : 28 participants
Observational Model: Cohort
Time Perspective: Prospective
Study Start Date : September 2014
Actual Primary Completion Date : November 2014
Actual Study Completion Date : November 2014

Primary Outcome Measures :
  1. ultrasonographic measurement of antral area [ Time Frame: 30 minutes and immediately before erythromycin infusion, and 30, 60 and 90 min after the start of erythromycin infusion ]

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Ages Eligible for Study:   18 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population
all trauma patients with a full stomach, undegoing emergency surgery

Inclusion Criteria:

  • Emergency surgery for trauma
  • ASA 1 and 2 patients
  • Full stomach (antral area > 550 mm²)
  • Adult patients

Exclusion Criteria:

  • No contraindication to erythromycin
  • Extreme emergency surgery (time frame < 90 min between arrival in the service and the start of the surgery)
  • gastroparesis or pathology associated with gastroparesis

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT02296866

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Hopital Edouard Herriot
Lyon, France, 69003
Sponsors and Collaborators
Lionel Bouvet

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Responsible Party: Lionel Bouvet, MD PhD, Hôpital Edouard Herriot Identifier: NCT02296866     History of Changes
Other Study ID Numbers: 2013-A01257-38
First Posted: November 20, 2014    Key Record Dates
Last Update Posted: December 30, 2014
Last Verified: December 2014
Additional relevant MeSH terms:
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Disease Attributes
Pathologic Processes