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Prediction of Fluid Responsiveness Using Dynamic Preload Indices During Arthroscopic Shoulder Surgery in the Beach Chair Position

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT02291185
Recruitment Status : Completed
First Posted : November 14, 2014
Last Update Posted : September 1, 2015
Information provided by (Responsible Party):
Yonsei University

Brief Summary:
The beach chair position (BCP) has been commonly used for shoulder arthroscopic surgery. Hemodynamic instability is frequently encountered problem associated with BCP. In addition, high rates of cerebral desaturation events have been reported during surgery in BCP. Although fluid loading could alleviate hypotension associated with BCP, it may lead to volume overload. As an alternative to static indices, dynamic preload indices such as pulse pressure variation (PPV) and stroke volume variation (SVV) were reported to be sensitive predictors of fluid responsivness in several surgical condition. The investigators will examine the abilities of PPV and SVV to predict fluid responsivness during shoulder arthroscopic surgery in BCP. Using transesophageal echocardiography (TEE), the investigators will directly estimate the change of cardiac output during BCP.

Condition or disease
Shoulder Arthroscopy

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Study Type : Observational
Actual Enrollment : 42 participants
Observational Model: Case-Only
Time Perspective: Prospective
Study Start Date : November 2014
Actual Primary Completion Date : July 2015
Actual Study Completion Date : July 2015

Primary Outcome Measures :
  1. The changes between dynamic preload indices (SVV and PPV) and stroke volume index during beach chair position. We will measure them to evaluate the effect of beach chair position on PPV and SVV. [ Time Frame: The participants will be followed up to 5 minutes after fluid challenge. ]
    To investigate the ability of SVV adn PPV to predict fluid responsiveness during beach chair position, using ROC curve.

Information from the National Library of Medicine

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Ages Eligible for Study:   20 Years to 75 Years   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
patients undergoing shoulder arthroscopic surgery in the beach chair position

Inclusion Criteria:

  1. Above 20 years of age.
  2. American Society of Anesthesiologists (ASA) Physical Status I, II, III.
  3. shoulder arthroscopy under Beach-chair position

Exclusion Criteria:

  1. severe functional liver or kidney disease
  2. diagnosed HF ( NYHA class >3)
  3. cerebrovascular disease 4. Pregnancy
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Responsible Party: Yonsei University Identifier: NCT02291185    
Other Study ID Numbers: 4-2014-0698
First Posted: November 14, 2014    Key Record Dates
Last Update Posted: September 1, 2015
Last Verified: August 2015