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Oscillation Mechanics of the Respiratory System Asbestos Exposed: Early Diagnosis

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ClinicalTrials.gov Identifier: NCT02280343
Recruitment Status : Unknown
Verified June 2015 by Paula Morisco de Sá, Rio de Janeiro State University.
Recruitment status was:  Recruiting
First Posted : October 31, 2014
Last Update Posted : July 1, 2015
Sponsor:
Information provided by (Responsible Party):
Paula Morisco de Sá, Rio de Janeiro State University

Brief Summary:
Inhalation of dust containing asbestos results in a process of interstitial pulmonary fibrosis called asbestosis. The Forced Oscillation Technique (FOT) evaluates the respiratory mechanics describing resistive, elastic and inertial properties. We believe that this technique may contribute to the early diagnosis of asbestosis.

Condition or disease Intervention/treatment
Asbestosis Other: evaluated lung function

Detailed Description:

The aims of this study were (1) to use the FOT to analyze how respiratory mechanics is affected in patients with asbestos exposed, (2) to identify the best FOT parameters for the diagnosis of respiratory changes in these patients (3) Assess whether the presence of obstructive changes is associated with the smoking habit.The control group (CG) included 24 subjects with normal spirometric data and without a history of smoking or pulmonary disease formed by workers and students UERJ and FioCruz. Volunteers with asbestos exposure were from the Department of CESTEH/ FioCruz, totaling 24 exposed and 7 with diagnoses of asbestosis.

The diagnosis of asbestosis was established based on a history of substantial exposure to asbestos dusts and compatible radiological features, together with exclusion of other competing diagnoses.

The tests included a standardized questionnaire on respiratory symptoms, clinical evaluation; Plain radiography of the chest; FOT, plethysmography and spirometry, in that order.

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Study Type : Observational
Estimated Enrollment : 2 participants
Time Perspective: Cross-Sectional
Official Title: OSCILLATION MECHANICS OF THE RESPIRATORY SYSTEM ASBESTOS EXPOSED : Early Diagnosis
Study Start Date : March 2013
Estimated Primary Completion Date : March 2016
Estimated Study Completion Date : March 2016

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Asbestos


Intervention Details:
  • Other: evaluated lung function
    lung function tests


Primary Outcome Measures :
  1. changes in pulmonary mechanicals [ Time Frame: 1 year ]


Information from the National Library of Medicine

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Ages Eligible for Study:   Child, Adult, Older Adult
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Probability Sample
Study Population
exposed to asbesto
Criteria

Inclusion Criteria:

  • diagnosis of asbestosis

Exclusion Criteria:

  • other diseases

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02280343


Contacts
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Contact: Paula Sá, research 552123340705 paulamorisco@hotmail.com

Locations
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Brazil
Paula Morisco de Sá Recruiting
Rio de Janeiro, Brazil, 20550-013
Contact: Paula M de Sá, researcher    552123340705    paulamorisco@hotmail.com   
Sponsors and Collaborators
Rio de Janeiro State University
Investigators
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Principal Investigator: Paula Sá, research Universidade do Estado do Rio de Janeiro:Brazil
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Responsible Party: Paula Morisco de Sá, OSCILLATION MECHANICS OF THE RESPIRATORY SYSTEM ASBESTOS EXPOSED : Early diagnosis, Rio de Janeiro State University
ClinicalTrials.gov Identifier: NCT02280343    
Other Study ID Numbers: UERJ
First Posted: October 31, 2014    Key Record Dates
Last Update Posted: July 1, 2015
Last Verified: June 2015
Keywords provided by Paula Morisco de Sá, Rio de Janeiro State University:
forced oscillation tecnique
lung function
asbestosis
Additional relevant MeSH terms:
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Asbestosis
Pneumoconiosis
Lung Diseases, Interstitial
Lung Diseases
Respiratory Tract Diseases
Lung Injury
Occupational Diseases