Using CBT to Probe Psychobiobehavioral Resilience to Post-trauma Psychopathology
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|ClinicalTrials.gov Identifier: NCT02279290|
Recruitment Status : Completed
First Posted : October 31, 2014
Last Update Posted : May 6, 2019
|Condition or disease||Intervention/treatment||Phase|
|Anxiety Depression||Behavioral: Healthy Mind Intervention (HMI) Behavioral: Healthy Body Intervention (HBI)||Not Applicable|
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||50 participants|
|Intervention Model:||Parallel Assignment|
|Masking:||None (Open Label)|
|Official Title:||Using CBT to Probe Psychobiobehavioral Resilience to Post-trauma Psychopathology|
|Actual Study Start Date :||July 13, 2015|
|Actual Primary Completion Date :||November 14, 2018|
|Actual Study Completion Date :||April 26, 2019|
Experimental: Healthy Mind Intervention (HMI)
This intervention will focus on teaching individuals a way to manage acute and chronic stressors more effectively.
Behavioral: Healthy Mind Intervention (HMI)
Healthy Mind Intervention (HMI) is a flexible cognitive-behavioral resilience building program. Participants will receive 8 weekly, 60-minute individual sessions of HMI. In HMI, participants will be able to select 3 areas of resilience that they want to work on.
Active Comparator: Healthy Body Intervention (HBI)
This intervention will focus on important health-related topics.
Behavioral: Healthy Body Intervention (HBI)
The 8 weekly, 60-minute individual sessions will include the following topics: the mind-body connection, nutrition, exercise, unhealthy substances, sleep, preventing illness, and preventive care. Each session is spent providing didactic information on these topics and strategies for how to engage in behavior change in these areas.
- Psychological resilience outcomes include emotion regulation (DERS), hardiness (CD-RISC), optimism (LOT-R), perceived control (SMS), social support (MSPSS), and task-oriented coping (CISS-SFT). [ Time Frame: 0 - 9 weeks ]Difference between the interventions in the change of psychological resilience from pre to post intervention.
- Biological resilience outcomes include neuropeptide Y [NPY], dehydroepiandrosterone [DHEA], allopregnanolone [ALLO] taken from a blood draw. [ Time Frame: 0-9 weeks ]Difference between the interventions in the change of biological resilience from pre to post intervention.
- Extinction learning will be analyzed using the fear potentiated startle data from a fear conditioning paradigm. [ Time Frame: 0-9 weeks ]Difference between the interventions in the change of extinction learning from pre to post intervention.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02279290
|United States, Illinois|
|Rush University Medical Center|
|Chicago, Illinois, United States, 60612|
|Principal Investigator:||Alyson K Zalta, PhD||Rush University Medical Center|