Neuropathic Pain and Quality of Life in ICU Survivors (NEUPAQ)
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|ClinicalTrials.gov Identifier: NCT02279212|
Recruitment Status : Completed
First Posted : October 31, 2014
Last Update Posted : March 4, 2020
Previous research on intensive care unit (ICU) survivors shows that rehabilitation is challenging, because of patients experiences of disease related problems both under and after treatment. Approximately 20 % of patients die within hospital, up to 80% suffer from hallucinations and nightmares, deal with paranoiac experiences, chronic pain and other symptoms and disability (Angus et al 2004; De Letter et al 2001; Ely et al 2001; Nelson et al 2006; Van den Berghe et al 2001; Van den Berghe et al 2003) . A recent study shows that 28% of intensive care survivors have chronic pain that reduce their health related quality of life (Boyle et al 2004).
The aim of this study is to perform a survey about prevalence of pain type, and which consequences this causes when it comes to function and quality of life up to 12 months after the ICU stay.
- What type of pain has ICU survivors and how do pain change over time, related to treatment/rehabilitation and the illness' development?
- What is the relationship between different pain characteristic, quality of life, anxiety, depression, fatigue, sleep and PTSD in these patients?
- What is these patients largest obstacle for good QoL after discharge from hospital?
|Condition or disease|
A prospective and longitudinal survey 3 time points for data collection:
- ICU - background data about the patients ICU stay (days on ventilator, medication, treatment, SAPS II, SOFA etc).
- 3 months after ICU discharge - survey about pain, QoL, sleep, fatigue, Post traumatic stress disorder (PTSD), anxiety and depression.
- One year after ICU discharge - the same as 3 months.
Pain - Brief Pain Inventory, Neuropathic Pain Syndrome Inventory, Pain diary QoL - SF 12, Sleep - General Sleep Disorder Scale Fatigue - Lee Fatigue Scale Anxiety and depression - Hospital Anxiety and Depression Scale PTSD - PTSS 10 Social Provision - Revised Social Provision Scale
|Study Type :||Observational|
|Actual Enrollment :||127 participants|
|Official Title:||Neuropathic Pain and Quality of Life in ICU Survivors|
|Study Start Date :||May 2010|
|Actual Primary Completion Date :||April 30, 2018|
|Actual Study Completion Date :||September 6, 2018|
- Do pain change over time in ICU survivors meassured with BPI and NPSI? [ Time Frame: 1year after ICU discharge ]We will compare the results from 3 months with 1 year and look for differences.
- What is the relationship between patients self reported experience of pain and neurophysiological findings? [ Time Frame: 3 months after ICU discharge ]
- What is the relationship between patients self reported experience of pain and neurophysiological findings? [ Time Frame: 1 year after ICU discharge ]
- How are ICU survivors health related quality of life meassured with SF12? [ Time Frame: 3 months after ICU discharge ]
- How are ICU survivors health related quality of life meassured with SF 12? [ Time Frame: 1 year after ICU discharge ]
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02279212
|Oslo University Hospital|
|Oslo, Norway, 0424|
|Principal Investigator:||Audun Stubhaug, MD PhD||Oslo University Hospital|