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Comparison of Spinal Kinematics Between Asymptomatic Subjects and Patients With Low Back Pain

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ClinicalTrials.gov Identifier: NCT02278549
Recruitment Status : Completed
First Posted : October 30, 2014
Last Update Posted : October 27, 2015
Sponsor:
Collaborators:
University of Brighton
University of Lausanne Hospitals
Information provided by (Responsible Party):
Guillaume Christe, Haute Ecole de Santé Vaud

Brief Summary:

Low back pain (LBP) is a complex and common problem with major societal repercussions. Clinical evaluations, and especially functional assessments, are necessary for proper diagnosis and decisions on the most appropriate treatment. The assessment of lumbar kinematics has been frequently described. For instance, measures of range of motion (ROM), angular velocities and acceleration of the total lumbar spine (TLx) have demonstrated some differences between healthy subjects and LBP patients. However, recent evidence has suggested that models evaluating the TLx are insufficient. In fact, regional differences in kinematics have been described between the upper lumbar spine and the lower lumbar spine.

The aim of this study is to evaluate the differences in spinal kinematics between healthy subjects and LBP patients using a multi-segment model of the spine that allows regional analysis.


Condition or disease
Low Back Pain

Detailed Description:
A case-controlled study will be performed to compare asymptomatics subjects and patients with low back pain. ROM, angular velocities and coordination of the spine will be collected in a laboratory with a camera-based system (VICON). Subjects will have to perform normal ROM assessment in the three anatomical planes, as well as different functional activities such as sit to stand, step and walking. The measurement session will occur on one occasion for each participant.

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Study Type : Observational
Actual Enrollment : 22 participants
Observational Model: Case Control
Time Perspective: Cross-Sectional
Official Title: Comparison of Spinal Kinematics Between Asymptomatic Subjects and Patients With Low Back Pain Using a Multi-segment Model
Study Start Date : November 2014
Actual Primary Completion Date : June 2015
Actual Study Completion Date : June 2015

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Back Pain

Group/Cohort
Asymptomatic
Individuals between 30 and 50 years old that have had no episode of low back pain in the last two years requiring medical attention
Patients with Low Back Pain
Individuals between 30 and 50 years old that present with non-specific low back pain for more than 3 months



Primary Outcome Measures :
  1. Spinal kinematics [ Time Frame: Participants will be measured once ]
    kinematics of the spine and pelvis will be measured with a camera-based system. Markers will be placed to have different segments of the spine (lower lumbar spine, upper lumbar spine, lower thoracic spine, upper thoracic spine). Variables such as range of motion, angular velocities or coordination (among others) will be measured.


Secondary Outcome Measures :
  1. Score of disability [ Time Frame: Participants will be measured once ]
    Oswestry Disability Index. Outcome used primarily for description of the population and correlational analysis

  2. Score of kinesophobia [ Time Frame: Participants will be measured once ]
    Tampa Scale of kinesophobia. Outcome used primarily for description of the population and correlational analysis

  3. Score of risk of poor outcomes [ Time Frame: Participants will be measured once ]
    Start Back Tool. Outcome used primarily for description of the population and correlational analysis

  4. Pain intensity [ Time Frame: Participants will be measured once ]
    Numeric Pain Rating Scale (NPRS). Outcome used primarily for description of the population and correlational analysis



Information from the National Library of Medicine

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Ages Eligible for Study:   30 Years to 50 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
Patients with recurrent low back pain (more than months in duration) recruited through physiotherapy practices and medical consultations in the area of Lausanne, Switzerland.
Criteria

Inclusion Criteria:

  • Sufficient French level
  • BMI between 18 and 27
  • Non-specific low back pain for more than 3 months (pain provoked by movements, postures or activities)

Exclusion Criteria:

  • Pregnancy
  • Spondylolisthesis
  • Infection
  • Rheumatological or neurological diseases
  • Spinal fractures
  • Known spinal deformation (scoliosis, …)
  • Back surgery
  • Tumours
  • Radicular symptoms (with neurological signs). Pain irradiating in the lower limbs with decrease strength, sensitivity and reflex.
  • High level of pain (severity and irritability) at the time of experiment that prevents repeated movements.
  • Other concomitant pain or condition that could compromise the evaluation of lumbar kinematics.

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02278549


Locations
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Switzerland
University of Lausanne Hospitals
Lausanne, Vaud, Switzerland, 1011
Sponsors and Collaborators
Haute Ecole de Santé Vaud
University of Brighton
University of Lausanne Hospitals
Investigators
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Study Director: Julien Favre, PhD University of Lausanne Hospitals
Study Director: Lucy Redhead, PhD University of Brighton
Principal Investigator: Guillaume Christe, PT Haute Ecole de Santé Vaud

Publications:

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Responsible Party: Guillaume Christe, PT, Haute Ecole de Santé Vaud
ClinicalTrials.gov Identifier: NCT02278549    
Other Study ID Numbers: MT001GC
First Posted: October 30, 2014    Key Record Dates
Last Update Posted: October 27, 2015
Last Verified: October 2015
Keywords provided by Guillaume Christe, Haute Ecole de Santé Vaud:
Spinal kinematics
Additional relevant MeSH terms:
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Back Pain
Low Back Pain
Pain
Neurologic Manifestations
Signs and Symptoms