Study of Inflammatory Role of Epstein-Barr Virus (EBV) in Atrophic and Erosive Forms of Oral Lichen Planus (LICHENVIR)
|ClinicalTrials.gov Identifier: NCT02276573|
Recruitment Status : Unknown
Verified July 2015 by Centre Hospitalier Universitaire de Nice.
Recruitment status was: Recruiting
First Posted : October 28, 2014
Last Update Posted : October 26, 2015
Oral lichen planus (OLP) is a chronic inflammatory and relapsing. The average prevalence is 1 to 4%. The clinics forms are many and symptoms are varied. The erosive form, painful and debilitating is characterized by erosive areas, ulcerated on an erythematous base with or without a keratinocyte lichenien network.
The literature data moving towards an autoimmune origin, but the pathophysiological mechanisms of OLP remain unknown.
This project represents the first part of a comprehensive project to examine the oral pathogenesis of different viruses (Herpes and papillomavirus HPV) and centered on Epstein-Barr Virus (EBV).
|Condition or disease||Intervention/treatment||Phase|
|Lichen Planus, Oral||Biological: buccal cavity sample||Not Applicable|
|Study Type :||Interventional (Clinical Trial)|
|Estimated Enrollment :||15 participants|
|Intervention Model:||Single Group Assignment|
|Masking:||None (Open Label)|
|Primary Purpose:||Basic Science|
|Official Title:||Study of Inflammatory Role of Epstein-Barr Virus (EBV) in Atrophic and Erosive Forms of Oral Lichen Planus|
|Study Start Date :||March 2015|
|Estimated Primary Completion Date :||March 2016|
Experimental: Oral lichen planus disease
buccal cavity sample
Biological: buccal cavity sample
- Measure of level of EBV nucleic acids [ Time Frame: day 1 ]
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02276573
|Contact: Hélène RAYBAUD, MD||+(33)4 92 03 40 firstname.lastname@example.org|
|Hôpital saint Roch||Recruiting|
|Nice, France, 06000|
|Contact: Hélène RAYBAUD, MD +(33)4 92 03 40 11 email@example.com|