Evaluation of Conventional Antibiotic Prophylaxis During a Change of Hip or Knee Infected at a Time
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|ClinicalTrials.gov Identifier: NCT02272205|
Recruitment Status : Unknown
Verified October 2014 by University Hospital, Strasbourg, France.
Recruitment status was: Not yet recruiting
First Posted : October 22, 2014
Last Update Posted : October 22, 2014
Infection is a serious complications after undergoing total hip replacement. It occurs in about 1% of cases. The optimal treatment of these infections is discussed. The team validated by international publications change strategy of the infected prosthesis at a time.
Antibiotic prophylaxis has significantly reduced the infection intraoperative contamination in orthopedic surgery rates. It must be conventionally administered before the surgical incision. In response to infection, it is typically recommended to start this antibiotic after the completion of the deep bacteriological samples, so as not to negate the risk of these samples by the prior administration of antibiotics. This attitude, however, is not formally validated by the scientific literature. In contrast, two recent publications challenge this practice, and suggest the use of a conventional antibiotic prophylaxis even in septic interventions. Our multidisciplinary team opted for a few months for this new strategy. We wish to evaluate the influence of this new approach results in the treatment of infection in total hip or knee.
|Condition or disease||Intervention/treatment|
|Total Hip Replacement||Other: Retrospective analysis of records|
|Study Type :||Observational|
|Estimated Enrollment :||80 participants|
|Official Title:||Evaluation of the Effect of a Conventional Antibiotic Prophylaxis on the Positivity of Intraoperative Bacteriological Samples During a Change of Hip or Knee Infected at a Time|
|Study Start Date :||November 2014|
|Estimated Primary Completion Date :||October 2015|
|Estimated Study Completion Date :||October 2015|
- concordance of pre-and intraoperative bacteriological documentation [ Time Frame: preoperative; intraoperative ]concordance of pre-and intraoperative bacteriological documentation (division into 3 classes: complete, partial, no - Chi-square test
- rates to relapse of the initial infection or a new infection [ Time Frame: preoperative; intraoperative ]rates to relapse of the initial infection or a new infection (survival curves according to Kaplan-Meier with log-rank test)
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Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02272205
|Contact: Jean-Yves JENNY, MDfirstname.lastname@example.org|