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The Effect of Dexamethasone Dosing on Post-tonsillectomy Hemorrhage

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT02228135
Recruitment Status : Completed
First Posted : August 28, 2014
Last Update Posted : July 26, 2017
Information provided by (Responsible Party):
Nicole Elsey, Nationwide Children's Hospital

Brief Summary:
This is a retrospective chart review looking at the effect of dexamethasone dosing on post-tonsillectomy hemorrhage.

Condition or disease Intervention/treatment
Tonsillectomy Adenotonsillectomy Drug: Dexamethasone

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Study Type : Observational
Actual Enrollment : 9843 participants
Observational Model: Cohort
Time Perspective: Retrospective
Study Start Date : September 2014
Actual Primary Completion Date : February 2017
Actual Study Completion Date : February 2017

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Bleeding Tonsillitis

Group/Cohort Intervention/treatment
Non post-tonsillectomy hemorrhage
Children who do not have post-tonsillectomy hemorrhage.
Drug: Dexamethasone
Post-tonsillectomy hemorrhage
Children return to the hospital after surgery with post-tonsillectomy hemorrhage.
Drug: Dexamethasone

Primary Outcome Measures :
  1. Dexamethasone Dosage [ Time Frame: once at start of surgery ]

Information from the National Library of Medicine

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Ages Eligible for Study:   Child, Adult, Older Adult
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Children who have had tonsillectomy or adenotonsillectomy

Inclusion Criteria:

  • Patients undergoing a tonsillectomy
  • Patients undergoing an adenotonsillectomy

Exclusion Criteria:

  • All patients with a known history of bleeding or clotting disorders, as well as those patients who had presented to Nationwide Children's Hospital main operating room for control of PTH but had their initial tonsillectomy/adenotonsillectomy at an outlying facility will be excluded from the study.

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT02228135

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United States, Ohio
Nationwide Children's Hospital
Columbus, Ohio, United States, 43205
Sponsors and Collaborators
Nicole Elsey

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Responsible Party: Nicole Elsey, Clinical Assistant Professor, Nationwide Children's Hospital Identifier: NCT02228135     History of Changes
Other Study ID Numbers: IRB14-00588
First Posted: August 28, 2014    Key Record Dates
Last Update Posted: July 26, 2017
Last Verified: July 2017
Additional relevant MeSH terms:
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Dexamethasone acetate
BB 1101
Anti-Inflammatory Agents
Autonomic Agents
Peripheral Nervous System Agents
Physiological Effects of Drugs
Gastrointestinal Agents
Hormones, Hormone Substitutes, and Hormone Antagonists
Antineoplastic Agents, Hormonal
Antineoplastic Agents
Protease Inhibitors
Enzyme Inhibitors
Molecular Mechanisms of Pharmacological Action