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Age-related Cognitive Change of Femur

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT02220322
Recruitment Status : Unknown
Verified October 2016 by Toshihiko Kono, Tomidahama Hospital.
Recruitment status was:  Recruiting
First Posted : August 19, 2014
Last Update Posted : October 19, 2016
Information provided by (Responsible Party):
Toshihiko Kono, Tomidahama Hospital

Brief Summary:
Age-related change of femur is not well-known. The investigators investigated the longitudinal changes of femur.

Condition or disease

Detailed Description:

Recently, bisphosphonate-related atypical fracture of femur (AFF) is paid attention in clinicians. Almost all AFFs were occurred in thicker cortical thickness. But age-related change of femur is not well-known.

The main objective of this study is to reveal the age-related change of femur.

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Study Type : Observational [Patient Registry]
Estimated Enrollment : 1000 participants
Observational Model: Cohort
Time Perspective: Prospective
Target Follow-Up Duration: 1 Year
Official Title: Age-related Cognitive Change of Femur
Study Start Date : October 2013
Estimated Primary Completion Date : December 2016
Estimated Study Completion Date : July 2017

Primary Outcome Measures :
  1. Age-related change of femur [ Time Frame: Up to 12 months ]

    We investigate radiographic features in patients with osteopenia/opsteoporosis. We investigate bilateral femur radiographs concerning to cortical thickening. We analyze age-related change of femur.

    To determine the age-related change of femur , statistical analyses are performed using Spearman correlation, paired t-test, chi-square test, Fisher's exact test and Mann-Whitney U test. Finally, we conclude the effects of age on femur.

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Ages Eligible for Study:   40 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Probability Sample
Study Population
Osteoporosis or osteopenia patients

Inclusion Criteria:

  • Osteoporosis or osteopenia patients who presented to our hospital

Exclusion Criteria:

  • Patients without osteoporosis or osteopenia

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT02220322

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Contact: Rui Niimi, MD, PhD (81)-59-365-0023

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Tomidahama Hospital Recruiting
Yokkaichi, Mie, Japan, 510-8008
Contact: Rui Niimi, MD, PhD    (81)-59-365-0023   
Sponsors and Collaborators
Tomidahama Hospital
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Principal Investigator: Rui Niimi, PhD Tomidahama Hospital
Additional Information:

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Responsible Party: Toshihiko Kono, Head of Hospital, Tomidahama Hospital Identifier: NCT02220322    
Other Study ID Numbers: IRB TH No 9
First Posted: August 19, 2014    Key Record Dates
Last Update Posted: October 19, 2016
Last Verified: October 2016
Keywords provided by Toshihiko Kono, Tomidahama Hospital:
cortical thickness
Additional relevant MeSH terms:
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Bone Diseases, Metabolic
Bone Diseases
Musculoskeletal Diseases
Metabolic Diseases