Autologous Bone Marrow Derived Mesenchymal Stromal Cells (BM-MSCs) in Patients With Chronic Kidney Disease (CKD)
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|ClinicalTrials.gov Identifier: NCT02195323|
Recruitment Status : Completed
First Posted : July 21, 2014
Last Update Posted : January 5, 2016
|Condition or disease||Intervention/treatment||Phase|
|Chronic Kidney Disease||Biological: Intravenous injection||Phase 1|
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||7 participants|
|Intervention Model:||Single Group Assignment|
|Masking:||None (Open Label)|
|Official Title:||Administration of Autologous Bone Marrow Mesenchymal Stem Cells (BM-MSCs) in Patients With Chronic Kidney Disease (CKD)|
|Study Start Date :||April 2014|
|Actual Primary Completion Date :||December 2015|
|Actual Study Completion Date :||January 2016|
Experimental: MSC recipient
The patients with CKD who underwent intravenous injection of MSC.
Biological: Intravenous injection
Intravenous injection of bone marrow derived MSC in patients with CKD.
Other Name: Intravenous transplantation
- mass formation [ Time Frame: 6months ]Evaluation the probability of mass formation due to MSC transplantation 6 months after cell injection.
- Creatinin [ Time Frame: 1 month ]Evaluation the rise of creatinin 1 month after cell transplantation.
- GFR [ Time Frame: 6months ]Evaluation the increase of GFR 6 months after cell transplantation with scan isotope .
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02195323
|Iran, Islamic Republic of|
|Tehran, Iran, Islamic Republic of|
|Study Chair:||Hamid Gourabi, PhD||Head of Royan Institute|
|Study Director:||Nasser Aghdami, MD,PhD||Head of regenerative medicine department &cell therapy center of Royan Institute|
|Study Director:||Atieh Makhloogh, MD||Mazandaran University of Medical Sciences, Mazandaran, Iran|
|Principal Investigator:||Reza Moghadasali, PhD||Department of Regenerative Medicine And Royan Cell Therapy Center Royan Institute For stem Cell Biology and Technology|