Comparison of Acupuncture and Fluoxetine on Quality of Life in Menopausal Women
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ClinicalTrials.gov Identifier: NCT02188225 |
Recruitment Status :
Enrolling by invitation
First Posted : July 11, 2014
Last Update Posted : February 15, 2019
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Condition or disease | Intervention/treatment | Phase |
---|---|---|
Hot Flash Quality of Life | Procedure: acupuncture Drug: fluoxetine | Not Applicable |
Study Type : | Interventional (Clinical Trial) |
Estimated Enrollment : | 140 participants |
Allocation: | Randomized |
Intervention Model: | Parallel Assignment |
Masking: | Single (Participant) |
Primary Purpose: | Treatment |
Official Title: | Comparison of the Effects of Acupuncture and Fluoxetine on Quality of Life in Menopausal Women |
Study Start Date : | July 2014 |
Estimated Primary Completion Date : | February 20, 2019 |
Estimated Study Completion Date : | December 2019 |

Arm | Intervention/treatment |
---|---|
Experimental: Acupuncture
12 sessions of acupuncture / 3 sessions weekly/ 20 minutes each session
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Procedure: acupuncture
12 sessions acupuncture during 12 weeks (3 sessions weekly), each session lasting 20 minutes
Other Name: Manual acupuncture |
Active Comparator: fluoxetine
10 mg daily
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Drug: fluoxetine
10 mg/ daily
Other Name: flouxetine |
- Quality of life in menopausal women [ Time Frame: 3 months after start sampling ]Quality of life using MENQOL questionnaire

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Ages Eligible for Study: | Child, Adult, Older Adult |
Sexes Eligible for Study: | Female |
Accepts Healthy Volunteers: | Yes |
Inclusion Criteria:
- Last menstrual cycle 12 months ago
- natural menopause
- 4 episodes of hot flash daily
- follicle stimulating hormone (FSH)= 30-110 IU/L , E2<18pg/ml
- thyroid-stimulating hormone(TSH)= 0.4-4/0 IU/ml
- No using of herbal agent for treatment of hot flash
- having score in Beck depression Inventory<10
- No existence of any medical problems and using drugs
Exclusion Criteria:
- Not completing all acupuncture sessions
- Not completing fluoxetine admission
- Withdraw the study

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02188225
Iran, Islamic Republic of | |
Gonabad University of Medical Sciences | |
Gonabad, Khorasan Razavi, Iran, Islamic Republic of | |
Narjes Bahri | |
Mashhad, Razavi Hkorasan Privience, Iran, Islamic Republic of |
Principal Investigator: | Narjes Bahri, PhD Student | Gonabad University of Medical Sciences |
Responsible Party: | Narjes Bahri, Instructor of midwifery education, Gonabad University of Medical Sciences |
ClinicalTrials.gov Identifier: | NCT02188225 |
Other Study ID Numbers: |
GMU.REC.1393.56 |
First Posted: | July 11, 2014 Key Record Dates |
Last Update Posted: | February 15, 2019 |
Last Verified: | February 2019 |
Individual Participant Data (IPD) Sharing Statement: | |
Plan to Share IPD: | Undecided |
Hot flash Acupuncture Fluoxetine Quality of life |
Hot Flashes Fluoxetine Serotonin Uptake Inhibitors Neurotransmitter Uptake Inhibitors Membrane Transport Modulators Molecular Mechanisms of Pharmacological Action Neurotransmitter Agents Serotonin Agents |
Physiological Effects of Drugs Antidepressive Agents, Second-Generation Antidepressive Agents Psychotropic Drugs Cytochrome P-450 CYP2D6 Inhibitors Cytochrome P-450 Enzyme Inhibitors Enzyme Inhibitors |