The Lipid Profile of the Skin Surface in Acne (Acne)
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|ClinicalTrials.gov Identifier: NCT02180425|
Recruitment Status : Completed
First Posted : July 2, 2014
Last Update Posted : May 30, 2017
|Condition or disease||Intervention/treatment|
|Acne||Drug: Tretinoin or Adapalene Drug: Isotretinoin|
|Study Type :||Observational|
|Actual Enrollment :||30 participants|
|Official Title:||The Lipid Profile of the Skin Surface in Acne|
|Study Start Date :||November 2013|
|Actual Primary Completion Date :||May 2015|
|Actual Study Completion Date :||July 2015|
The subjects in this group do not have a history of acne.
Acne Group, Topical Retinoid
These subjects have been prescribed a topical retinoid for their acne. They will participate in the study for a period of 1 month.
Drug: Tretinoin or Adapalene
Subjects will apply a pea sized amount of topical retinoid cream once daily at night for 30 days. Subjects will return for a follow-up visit.
Other Name: Retin A
Acne Group, Isotretinoin
These subjects have been prescribed isotretinoin for their acne. They will participate in the study for a period of 5-6 months.
Subjects will take one pill once daily for 5 months. Subjects will return after 1 month and after 4-5 months of treatment for skin lipid profiling.
Other Name: Accutane
- Skin lipid profile of acne and healthy patients [ Time Frame: baseline visit ]Compare the skin lipid profile of acne and healthy patients at baseline
- Skin lipid profile of acne patients after treatment [ Time Frame: at 1 month and 4-5 months of treatment ]Patients in the topical retinoid group will have their lipids evaluated after 1 month of treatment. Patients in the systemic retinoid (isotretinoin) group will have their lipids evaluated after 1 and 4-5 months of treatment.
Biospecimen Retention: Samples Without DNA
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02180425
|United States, California|
|Dermatology Research Area|
|Davis, California, United States, 95616|
|UC Davis Department of Dermatology|
|Sacramento, California, United States, 95816|
|Principal Investigator:||Raja K Sivamani, MD||UC Davis|