Effects of Yoga on Bone Metabolism in Premenopausal Women
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|ClinicalTrials.gov Identifier: NCT02163668|
Recruitment Status : Completed
First Posted : June 16, 2014
Last Update Posted : June 16, 2014
|Condition or disease||Intervention/treatment||Phase|
|Bone Health Osteoporosis||Other: Yoga Group||Not Applicable|
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||47 participants|
|Intervention Model:||Parallel Assignment|
|Masking:||None (Open Label)|
|Official Title:||Effects of an 8-month Yoga Intervention on Bone Metabolism in Healthy Middle-aged Premenopausal Women: A Randomized Controlled Study|
|Study Start Date :||September 2009|
|Actual Primary Completion Date :||June 2010|
|Actual Study Completion Date :||April 2012|
Experimental: Yoga group
8 months of progressive Yoga training
Other: Yoga Group
8 months of Yoga training
No Intervention: Control group
No training, just pre and post testing
- Change in bone mineral density from baseline to 8 months [ Time Frame: pre and post 8 months training ]
- change in bone turnover markers [ Time Frame: pre and post 8 month intervention ]
- change in tibia bone characteristics [ Time Frame: pre and post 8 month intervention ]changes in volumetric bone mineral density and bone strength of the non-dominant tibia assessed by peripheral Quantitative Computed Tomography (pQCT)
- Changes in muscular strength [ Time Frame: pre and post 9 month intervention ]Isotonic 1 repetition maximum (1RM) for 4 lower body and 2 upper body resistance exercises
- Change in arterial compliance [ Time Frame: pre and post 8 month interventon ]Arterial compliance of the large and small arteries was assessed using Pulse Contour analysis.
- Change in Insulin-like Growth Factor-1 (IGF-I) and Insulin-like Growth Factor BP3 (IGFBP3) [ Time Frame: pre and post 8 month intervention ]
- Daily Calcium intake [ Time Frame: pre and post 8 month intervention ]Calcium intake is a potential confounding variable. Participants were encouraged to increase their calcium intakes if found to be low before the intervention began.
- Menstrual History [ Time Frame: pre and post 8 month intervention ]This information was used to monitor menstrual characteristics to ensure they were still premenopausal at the post test.
- Dietary intake [ Time Frame: At baseline at the same time as other outcomes, about 2 weeks before the beginning of the yoga training ]Three day dietary logs were recorded by participants before the exercise intervention. They were analyzed for caloric intake and nutrient composition using the Diet Analysis Plus 9 software.
- Change in physical activity levels [ Time Frame: pre and post 8 month intervention ]Physical activity levels estimated by the bone-specific physical activity (PA) questionnaire to monitor their PA outside of the intervention
- Change in body composition [ Time Frame: pre and post 8 month intervention ]
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02163668
|United States, Oklahoma|
|Department of Health and Exercise Science, University of Oklahoma|
|Norman, Oklahoma, United States, 73019|
|Principal Investigator:||Debra A Bemben, PhD||Department of Health and Exercise Science, University of Oklahoma|