Echocardiography in Septic Shock
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|ClinicalTrials.gov Identifier: NCT02135796|
Recruitment Status : Unknown
Verified June 2019 by Intermountain Health Care, Inc..
Recruitment status was: Recruiting
First Posted : May 12, 2014
Last Update Posted : June 13, 2019
BACKGROUND: Echocardiography can provide evaluation of right or left ventricular dysfunction and volume status during resuscitation of patients with sepsis and septic shock and guide intravenous vasopressor and fluid therapy. While there are numerous echocardiographic studies regarding cardiac function and volume status in patients with established shock, there are none that describe these during the early resuscitation of septic shock.
The study objective is to correlate echocardiographic findings with clinical parameters and net fluid balance measured during the early resuscitation of critically ill patients with sepsis and septic shock.
Aim 1) correlate echocardiographic findings of cardiac function with physiologic markers in the early hours of resuscitation
Aim 2) correlate cardiac function and fluid status with clinical outcomes
Aim 3) evaluate the change in cardiac function over time in patients with sepsis and septic shock
Aim 4) evaluate long term clinical outcomes for patients with sepsis and septic shock.
|Condition or disease||Intervention/treatment|
|Septic Shock Severe Sepsis||Other: Echocardiography|
|Study Type :||Observational|
|Estimated Enrollment :||700 participants|
|Official Title:||ICU Echocardiography in Resuscitation of Sepsis and Septic Shock|
|Study Start Date :||October 2008|
|Estimated Primary Completion Date :||December 2019|
|Estimated Study Completion Date :||December 2019|
Individuals who are admitted to the Intensive Care Unit (ICU) with an infection called Sepsis or Septic Shock. This group will receive transthoracic echocardiography as part of the study.
- Correlate echo findings and markers of resuscitation [ Time Frame: Within 12 hours of Intensive Care Unit admission ]Correlate echocardiographic findings of cardiac function with physiologic markers in the early hours of resuscitation. Specifically, cardiac markers will be analyzed in relation to cardiac function, including ejection fraction, strain, and diastolic function, and correlate these with several clinical parameters, including receipt of fluid, vasopressors, mechanical ventilation, and septic cardiomyopathy
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02135796
|Contact: Kimberly Rhodesfirstname.lastname@example.org|
|Contact: Michael Lanspa, MD||(801) 507-6554||Michael.Lanspa@imail.org|
|United States, Utah|
|Intermountain Medical Center||Recruiting|
|Murray, Utah, United States, 84157|
|Contact: Michael Lanspa, MD 801-507-6556|
|Principal Investigator: Michael Lanspa, MD|
|Principal Investigator:||Michael Lanspa, MD||Intermountain Health Care, Inc.|