The Role of Progesterone and PIF for Successful Implantation and On-going Pregnancy in Assisted Reproductive Technology
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.|
|ClinicalTrials.gov Identifier: NCT02129998|
Recruitment Status : Completed
First Posted : May 2, 2014
Last Update Posted : October 9, 2017
The aim of this study is to achieve a more profound understanding of the endocrine alteration in luteal progesterone level after gonadotrophin stimulated IVF/ICSI cycles and to explore the optimal progesterone level needed for securing implantation and development of early pregnancy.
The second part of the project will determine the value of Preimplantation Factor (PIF) measurement in embryo culture medium as a possible tool for improved embryo selection and the use of PIF as an early pregnancy serum marker for healthy implantation and embryo development.
IVF: In vitro fertilisation, ICSI: Intracytoplasmic sperm injection.
|Condition or disease||Intervention/treatment|
|Infertility||Other: IVF/ICSI treatment|
|Study Type :||Observational|
|Actual Enrollment :||873 participants|
|Official Title:||The Role of Luteal Progesterone and Preimplantation Factor (PIF) for Successful Implantation and On-going Pregnancy in Assisted Reproductive Technology|
|Actual Study Start Date :||May 2014|
|Actual Primary Completion Date :||July 2017|
|Actual Study Completion Date :||October 2017|
|Standard IVF/ICSI treatment||
Other: IVF/ICSI treatment
- On-going pregnancy rate [ Time Frame: 10th week of gestation ]
- Implantation rate [ Time Frame: 7th week of gestation ]
Biospecimen Retention: Samples Without DNA
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02129998
|The Fertility Clinic Skive|
|Skive, Denmark, 7800|