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Trial record 33 of 1478 for:    child psychiatry

Enhancing Behavior and Brain Response to Visual Targets Using a Computer Game

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ClinicalTrials.gov Identifier: NCT02118649
Recruitment Status : Recruiting
First Posted : April 21, 2014
Last Update Posted : June 5, 2019
Sponsor:
Information provided by (Responsible Party):
James C. McPartland, Yale University

Brief Summary:

Participants will play a computer game that is controlled by their gaze patterns and designed to direct attention their attention to specific on-screen targets. Visual attention to targets will be rewarded. Both visual behavior and brain response will be recorded during game play.

It is hypothesized that that, over the course of the game, relative to baseline, participants will show (a) increased looking to targets, (b) decreased response time to targets, and (c) enhanced, more efficient neural response to visual cues. It is hypothesized that clinical variability will associate with visual attention and brain response.


Condition or disease Intervention/treatment Phase
Neurodevelopmental Disorders Behavioral: Game Not Applicable

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Study Type : Interventional  (Clinical Trial)
Estimated Enrollment : 100 participants
Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Study Start Date : April 2014
Estimated Primary Completion Date : April 2022
Estimated Study Completion Date : April 2022

Arm Intervention/treatment
Experimental: Game
Participants will play a video game directing their gaze to on-screen targets.
Behavioral: Game



Primary Outcome Measures :
  1. EEG brain response to targets [ Time Frame: Measures will be recorded for the duration of their visit, an expected average of 3 hours. ]

Secondary Outcome Measures :
  1. Visual attention to targets as measured by eye-tracking [ Time Frame: Measures will be recorded for the duration of their visit, an expected average of 3 hours. ]
  2. Social Responsiveness Scale, Second Edition [ Time Frame: Measures will be collected during visit, an expected average of 3 hours. ]
  3. Autism Diagnostic Observation Schedule [ Time Frame: Measures will be collected during visit, an expected average of 3 hours. ]
  4. Differential Abilities Scale [ Time Frame: Measures will be collected during visit, an expected average of 3 hours. ]
  5. Vineland Adaptive Behavior Scales, Second Edition [ Time Frame: Measures will be collected during visit, an expected average of 3 hours. ]
  6. Social Anxiety Scale for Children, Revised [ Time Frame: Measures will be collected during visit, an expected average of 3 hours. ]


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Ages Eligible for Study:   Child, Adult, Older Adult
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • Able to participate in an eye-tracking experiment
  • Able to participate in an EEG experiment

Exclusion Criteria:

  • Sensory or physical impairment that would preclude completion of protocol
  • Participants taking prescription medications that may affect cognitive processes
  • Participants reporting significant head trauma or history of seizures

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02118649


Contacts
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Contact: Nicole R Wright, BS 203-785-3488 n.wright@yale.edu
Contact: Adam J Naples, PhD 203-737-4586 adam.naples@yale.edu

Locations
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United States, Connecticut
Yale Child Study Center Recruiting
New Haven, Connecticut, United States, 06520
Contact: Nicole R Wright, BS    203-785-3488    n.wright@yale.edu   
Principal Investigator: James C McPartland, PhD         
Sub-Investigator: Adam J Naples, PhD         
Sponsors and Collaborators
Yale University

Publications:
Constantino, J. N., & Gruber, C. P. (2012). The Social Responsiveness Scale, Second Edition. Los Angeles, CA: Western Psychological Services.
Lord, C., Rutter, M., DiLavore, P. C., & Risi, S. (1999). Autism Diagnostic Observation Schedule - WPS (ADOS-WPS), Los Angeles, CA: Western Psychological Services.
Elliott C. Differential Ability Scales: Second Edition (DAS-II). San Antonio, TX: Psychological Corporation. 2007.
Sparrow, S. S., Balla, D., Cicchetti, D. (1984). Vineland Adaptive Behavior Scales. Circle Pines, MN, American Guidance Service.

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Responsible Party: James C. McPartland, Assistant Professor of Child Psychiatry and Psychology, Yale University
ClinicalTrials.gov Identifier: NCT02118649     History of Changes
Other Study ID Numbers: 14-10788
First Posted: April 21, 2014    Key Record Dates
Last Update Posted: June 5, 2019
Last Verified: June 2019

Additional relevant MeSH terms:
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Neurodevelopmental Disorders
Mental Disorders