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Downhill Walking Training in COPD

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ClinicalTrials.gov Identifier: NCT02113748
Recruitment Status : Unknown
Verified April 2014 by Thierry Troosters, KU Leuven.
Recruitment status was:  Recruiting
First Posted : April 15, 2014
Last Update Posted : April 15, 2014
Sponsor:
Collaborators:
Research Foundation Flanders
Conselho Nacional de Desenvolvimento Científico e Tecnológico
Information provided by (Responsible Party):
Thierry Troosters, KU Leuven

Brief Summary:

This randomized control trial will investigate whether a modality that generates more contractile muscle fatigue with lower ventilatory requirements render better results after a 12-week exercise training program in subjects with COPD.

Subjects will be randomized to either exercise in a training program including downhill walking or to exercise in a training program including conventional walking.


Condition or disease Intervention/treatment Phase
Pulmonary Disease, Chronic Obstructive Other: Downhill walking training Other: Conventional walking training Not Applicable

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Study Type : Interventional  (Clinical Trial)
Estimated Enrollment : 42 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Official Title: Downhill Walking to Enhance Training Effects in Patients With COPD
Study Start Date : April 2014
Estimated Primary Completion Date : April 2015

Resource links provided by the National Library of Medicine

MedlinePlus related topics: COPD

Arm Intervention/treatment
Experimental: Downhill walking training
Exercise training including treadmill walking with a negative inclination.
Other: Downhill walking training
Walk on a treadmill with a negative inclination.

Active Comparator: Conventional walking training
Exercise training including treadmill walking without inclination. Possible to progress training intensity with positive inclinations.
Other: Conventional walking training
Walk on a treadmill without inclination. Possible to progress training intensity with positive inclinations




Primary Outcome Measures :
  1. changes in 6-minute walking distance [ Time Frame: changes from baseline to Week 12 ]


Information from the National Library of Medicine

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Ages Eligible for Study:   Child, Adult, Older Adult
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Patients with a primary diagnosis of COPD according to internationally accepted guidelines
  • Patients referred to the outpatient PR program of Gasthuisberg University Hospital(Leuven, Belgium)

Exclusion Criteria:

  • Any underlying disease or musculoskeletal limitation that could impair the ability to perform any of the exercise training modalities
  • Absence of exacerbations in the previous month before entering the present study
  • Patients included on the waiting list for lung transplantation

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02113748


Contacts
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Contact: Thierry Troosters, PhD Thierry.Troosters@kuleuven.be

Locations
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Belgium
University Hospitals Leuven Recruiting
Leuven, Vl-Brabant, Belgium, 3000
Contact: Thierry Troosters, PhD       Thierry.Troosters@kuleuven.be   
Sub-Investigator: Carlos Augusto Camillo, MSc         
Principal Investigator: Thierry Troosters, PhD         
Principal Investigator: Wim Janssens, MD, PhD         
Sponsors and Collaborators
KU Leuven
Research Foundation Flanders
Conselho Nacional de Desenvolvimento Científico e Tecnológico
Investigators
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Principal Investigator: Thierry Troosters, PhD KU Leuven

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Responsible Party: Thierry Troosters, Prof., KU Leuven
ClinicalTrials.gov Identifier: NCT02113748     History of Changes
Other Study ID Numbers: ML10278
First Posted: April 15, 2014    Key Record Dates
Last Update Posted: April 15, 2014
Last Verified: April 2014

Keywords provided by Thierry Troosters, KU Leuven:
Pulmonary disease, chronic obstructive
Downhill walking
exercise

Additional relevant MeSH terms:
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Lung Diseases
Chronic Disease
Pulmonary Disease, Chronic Obstructive
Respiratory Tract Diseases
Disease Attributes
Pathologic Processes
Lung Diseases, Obstructive