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Trial record 60 of 977 for:    scale | Norway

The Importance of Needle Gauge for Pain During Injection of Local Anaesthetic

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ClinicalTrials.gov Identifier: NCT02107729
Recruitment Status : Completed
First Posted : April 8, 2014
Last Update Posted : July 29, 2016
Sponsor:
Collaborator:
St. Olavs Hospital
Information provided by (Responsible Party):
Norwegian University of Science and Technology

Brief Summary:
This study will investigate the influence of needle gauge on pain during injection of local anaesthetic. Healthy volunteers will be recruited, who will each receive three injections with either 21G, 23G or 27G subcutaneously on the abdomen. After each injection, the participants will be asked to evaluate the pain on a Visual analog scale (0-100 mm). It is anticipated that the pain will decrease with decreasing thickness of the needle. The aim of this study is to find a simple method for pain reduction that can be used in clinical practice.

Condition or disease Intervention/treatment Phase
Needlestick Injuries Procedure: Large needle gauge lidocaine injection Procedure: Normal needle gauge lidocaine injection Procedure: Small needle gauge lidocaine injection Not Applicable

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Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 36 participants
Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: Single (Participant)
Primary Purpose: Treatment
Official Title: The Importance of Needle Gauge for Pain During Injection of Local Anaesthetic
Study Start Date : February 2014
Actual Primary Completion Date : June 2014
Actual Study Completion Date : June 2014

Arm Intervention/treatment
Experimental: Needle gauge small
injection needle 23 G
Procedure: Large needle gauge lidocaine injection
21 G

Procedure: Normal needle gauge lidocaine injection
23 G

Procedure: Small needle gauge lidocaine injection
27 G

Experimental: Needle gauge normal
injection needle 25 G
Procedure: Large needle gauge lidocaine injection
21 G

Procedure: Normal needle gauge lidocaine injection
23 G

Procedure: Small needle gauge lidocaine injection
27 G

Experimental: Needle gauge large
injection needle 27 G
Procedure: Large needle gauge lidocaine injection
21 G

Procedure: Normal needle gauge lidocaine injection
23 G

Procedure: Small needle gauge lidocaine injection
27 G




Primary Outcome Measures :
  1. Pain [ Time Frame: 60 seconds ]
    1. Visual analog scale
    2. Questionnaire



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Ages Eligible for Study:   18 Years to 65 Years   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • Age 18-65 years

Exclusion Criteria:

  • Kidney, heart or liver disease
  • Eczema or psoriasis on injection site
  • Neuropathy
  • Regular use of painkillers
  • Hypersensitivity of Lidocaine
  • Pregnancy
  • Diabetes

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02107729


Locations
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Norway
Department of Neuroscience, NTNU
Trondheim, Norway
Sponsors and Collaborators
Norwegian University of Science and Technology
St. Olavs Hospital
Investigators
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Study Director: Vilhjalmur Finsen, Prof md Norwegian University of Science and Technology

Publications of Results:
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Responsible Party: Norwegian University of Science and Technology
ClinicalTrials.gov Identifier: NCT02107729     History of Changes
Other Study ID Numbers: 2013/2297B
First Posted: April 8, 2014    Key Record Dates
Last Update Posted: July 29, 2016
Last Verified: July 2016

Keywords provided by Norwegian University of Science and Technology:
Injections
Pain
Healthy volunteers
Lidocaine

Additional relevant MeSH terms:
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Needlestick Injuries
Wounds, Stab
Wounds, Penetrating
Wounds and Injuries
Lidocaine
Anesthetics, Local
Anesthetics
Central Nervous System Depressants
Physiological Effects of Drugs
Sensory System Agents
Peripheral Nervous System Agents
Anti-Arrhythmia Agents
Voltage-Gated Sodium Channel Blockers
Sodium Channel Blockers
Membrane Transport Modulators
Molecular Mechanisms of Pharmacological Action