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Biomedical Instrumentation in the Study of Mirror Therapy in Elderly's Hands Motor Activity

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ClinicalTrials.gov Identifier: NCT02104102
Recruitment Status : Unknown
Verified March 2014 by Universidade do Vale do Paraíba.
Recruitment status was:  Recruiting
First Posted : April 4, 2014
Last Update Posted : April 4, 2014
Sponsor:
Information provided by (Responsible Party):
Universidade do Vale do Paraíba

Brief Summary:
Check if the Mirror therapy represents an effective method in improving the motor activity of the hands of institutionalized elderly.

Condition or disease Intervention/treatment Phase
Muscle Weakness Conditions Other: Mirror Therapy Other: Kinesiotherapy Not Applicable

Detailed Description:
Among the various functions impaired by aging there is the muscle function, which indirectly affects the quality of life for seniors, since it is crucial to the progressive increase of the debilitating condition, leading to difficulties in carrying out everyday tasks and often making them dependent on the assistance of others. The possible neural mechanisms underlying this decrease in muscle function associated with aging include changes undefined in Central Nervous System, a delay in conduction velocity of motor nerve fibers and in transmission of the neuromuscular junction. In this context, it is necessary to develop procedures that reduce the functional losses and decrease the negative effects of the aging process, increasing the quality of life for seniors. Mirror Therapy (MT) is the one of those possible procedures, which is based on the activation of mirror neurons from the illusion generated by viewing the reflection of a member in a mirror. When performing a movement with a member who is in your field of vision, generated the reflection in the mirror is able to offer the brain a new, albeit illusory visual stimulus, suggesting that covert member is moving. This illusion promotes the activation of mirror neurons located in the sensorimotor cortex region and the progression of therapy, this activation drives cortical plasticity that promotes the reestablishment of functions, such as motor coordination and increased range of motion. Therefore, MT is a promising technique to reduce the functional losses of aging. It is then suggested the implementation of a protocol for functional recovery of MT hands in institutionalized elderly and the measurement of electromyographic activity of the wrist, the range and speed of movement, the writing skill and the application of a questionnaire to Katz index calculation in order to investigate whether the technique can benefit this public.

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Study Type : Interventional  (Clinical Trial)
Estimated Enrollment : 60 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)
Official Title: Biomedical Instrumentation in the Study of Mirror Therapy in Elderly's Hands Motor Activity
Study Start Date : January 2014
Estimated Primary Completion Date : July 2014
Estimated Study Completion Date : December 2014

Arm Intervention/treatment
Experimental: Mirror group
Composed of 30 volunteers who carry out the mirror therapy, whose name shall Mirror Group (MG).
Other: Mirror Therapy
Mirror Therapy, which is based on the activation of mirror neurons from the illusion generated by viewing the reflection of a member in a mirror, that is, intended to facilitate the movement through the practice of bilateral symmetric activities, since it is able to stimulate cortical plasticity, promoting reversal of the decrease and the reestablishment of motor function.

Experimental: Control Group - kinesiotherapy
Called by Control Group (CG), composed of 30 volunteers who will carry out the kinesiotherapy with the same sequence of movements for the Mirror Therapy that the MG, but without the view in the mirror, since it will be blocked.
Other: Kinesiotherapy
Hands movements.




Primary Outcome Measures :
  1. Electromyography [ Time Frame: 6 weeks ]
    Muscle electrical activity will be assessed at two different times, one related to the collection along with the dynamometer and another related to the simultaneous collection accelerometer.It is expected that after treatment with Mirror Therapy for 2 weeks has been an improvement of sensorimotor functions, gain muscle strength , uniformity of muscle fiber recruitment and improves muscle synergy and gain in speed of movements.

  2. Dynamometry [ Time Frame: 6 weeks ]
    Manual strength will be assessed with the electromyography, asking the volunteer to perform the maximal volunteer contraction when pressing the portable manual dynamometer. It is expected that after treatment with Mirror Therapy for 2 weeks has been an improvement of muscle strength.

  3. Functionality [ Time Frame: 6 weeks ]
    The functionality will be measure by the Katz index during the period of the study.


Secondary Outcome Measures :
  1. Range of motion [ Time Frame: 6 weeks ]
    The range of motion will be taken for the movements of flexion and extension of the wrist.

  2. Writing skill [ Time Frame: 6 weeks ]
    The volunteers will writing a specified phrase and they will received a paper with four four geometric forms (square, triangle, circle and rhombus) to follow the line. This task should be done for both hands. The skill will be analysed by using a computer software developed to calculate the distances between the original line of the form and the line performed by the volunteer.



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Ages Eligible for Study:   60 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • 60 years old or more
  • Institutionalized elderly
  • Ability to understand and sign the Informed Consent Form. In case of illiteracy, the term will be read to the volunteer and signed by him in the case of functional illiteracy or by officials of the asylum
  • Ability to perform analysis of writing skills throughout the proposed protocol
  • Cognitive preserved, being able to respond to the examiner's command

Exclusion Criteria:

  • Disabling pain to perform movements with their arms
  • Active infection and rash at the application site of EMG
  • Severe uncorrected visual deficit
  • Deficit uncorrected severe hearing
  • Neurological disorders

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02104102


Contacts
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Contact: Rani S Alves, Graduate 5512981638109 rani.souzaalves@gmail.com
Contact: Mário O Lima, Professor 551239471000 ext 2066 mol@univap.br

Locations
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Brazil
Laboratory of Sensory and Motor Rehabilitation Engineering Recruiting
São José dos Campos, São Paulo, Brazil, 12244000
Contact: Rani S Alves, Masters    5512981638109    rani.souzaalves@gmail.com   
Contact: Mário O Lima, Professor    551239471000 ext 2066    mol@univap.br   
Principal Investigator: Rani S Alves, Graduate         
Sponsors and Collaborators
Universidade do Vale do Paraíba
Investigators
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Principal Investigator: Rani S Alves, Graduate Universidade do Vale do Paraíba

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Responsible Party: Universidade do Vale do Paraíba
ClinicalTrials.gov Identifier: NCT02104102     History of Changes
Other Study ID Numbers: 24581613.0.0000.5503
First Posted: April 4, 2014    Key Record Dates
Last Update Posted: April 4, 2014
Last Verified: March 2014
Keywords provided by Universidade do Vale do Paraíba:
Elderly
mirror therapy
hands
Additional relevant MeSH terms:
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Muscle Weakness
Muscular Diseases
Musculoskeletal Diseases
Neuromuscular Manifestations
Neurologic Manifestations
Nervous System Diseases
Pathologic Processes
Signs and Symptoms