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Liraglutide in Spinal Fluid (LIRA-CSV)

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
 
ClinicalTrials.gov Identifier: NCT02104037
Recruitment Status : Completed
First Posted : April 4, 2014
Last Update Posted : April 4, 2014
Sponsor:
Information provided by (Responsible Party):
Mikkel Christensen, University Hospital, Gentofte, Copenhagen

Study Description
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Brief Summary:
The purpose of this study is to investigate transfer of liraglutide from blood to cerebrospinal fluid.

Condition or disease Intervention/treatment Phase
Liraglutide Blood-brain Transfer Procedure: Lumbar puncture Not Applicable

Study Design
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Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 8 participants
Allocation: Non-Randomized
Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Basic Science
Official Title: Liraglutide in Spinal Fluid
Study Start Date : January 2012
Actual Primary Completion Date : December 2013

Resource links provided by the National Library of Medicine

Drug Information available for: Liraglutide

Arms and Interventions
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Arm Intervention/treatment
Experimental: Liraglutide treated patients Procedure: Lumbar puncture


Outcome Measures
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Primary Outcome Measures :
  1. cerebrospinal fluid concentration of liraglutide [ Time Frame: time 60 minutes ]

Eligibility Criteria
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Ages Eligible for Study:   18 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

Type 2 diabetes treated with liraglutide 1.8 mg for 1 month and 5% weight loss

Exclusion Criteria:

-

Contacts and Locations
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Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02104037


Locations
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Denmark
Diabetes Research Division, Department of Medicine
Hellerup, Denmark, 2900
Sponsors and Collaborators
Mikkel Christensen
More Information
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Responsible Party: Mikkel Christensen, Dr., University Hospital, Gentofte, Copenhagen
ClinicalTrials.gov Identifier: NCT02104037     History of Changes
Other Study ID Numbers: H-2-2011-027
First Posted: April 4, 2014    Key Record Dates
Last Update Posted: April 4, 2014
Last Verified: April 2014
Additional relevant MeSH terms:
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Liraglutide
Hypoglycemic Agents
Physiological Effects of Drugs
 Incretins
Hormones
Hormones, Hormone Substitutes, and Hormone Antagonists