C1q/TNF-related Proteins in Non-Alcoholic Fatty Liver Disease
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|ClinicalTrials.gov Identifier: NCT02083159|
Recruitment Status : Unknown
Verified September 2016 by Kyung Mook Choi, Korea University.
Recruitment status was: Recruiting
First Posted : March 11, 2014
Last Update Posted : September 21, 2016
Non-alcoholic fatty liver disease (NAFLD) is characterized by an accumulation of fat in the liver, which is one of the most common forms of chronic liver disease in developed countries. In western countries, the prevalence of NAFLD in the general population is estimated to be 20-30%; in obese populations, this increases to 57.5-74%. But, it hasn't been clearly elucidated yet regarding the underlying disease pathophysiology and treatmet strategy.
Recently, members of the C1q/tumor necrosis factor-related protein (CTRP) family have been reported to share structural homology with adiponectin. To date, 15 CTRP family members have been found that might play major roles in glucose metabolism and inflammation.
The investigators tried to clarify the relationship between CTRP family and NAFLD in Korean men and women.
|Condition or disease|
|Study Type :||Observational|
|Estimated Enrollment :||500 participants|
|Study Start Date :||March 2012|
|Estimated Primary Completion Date :||December 2016|
|Patients with NAFLD|
- serum concentration of CTRP-1, 3, or 9 in the subjects with/without NAFLD [ Time Frame: at enrollment ]
- The relationships of serum CTRPs/adiponectin levels with cardiometabolic risk profiles [ Time Frame: at enrollment ]
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02083159
|Contact: Ho Cheol Hong, M.D.||email@example.com|
|Contact: Kyung Mook Choi, M.D.||firstname.lastname@example.org|