Trial record 1 of 1 for:    Renal sympathetic denervation for reduction of pain and improvement
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Renal Sympathetic Denervation for Reduction of Pain and Improvement of Insulin Sensitivity in Adult Polycystic Kidney Disease

The recruitment status of this study is unknown because the information has not been verified recently.
Verified February 2014 by Odense University Hospital.
Recruitment status was  Recruiting
Information provided by (Responsible Party):
Hans Dieperink, Odense University Hospital Identifier:
First received: February 12, 2014
Last updated: February 13, 2014
Last verified: February 2014
In patients with polycystic kidney disease, pain may be resistant to drug therapy and may reduce quality of life. This study investigate the effect of renal denervation on this pain.

Condition Intervention
Adult Polycystic Kidney Disease
Procedure: renal denervation

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Safety/Efficacy Study
Intervention Model: Crossover Assignment
Masking: Open Label
Primary Purpose: Treatment

Resource links provided by NLM:

Further study details as provided by Odense University Hospital:

Primary Outcome Measures:
  • Pain [ Time Frame: 6 months ] [ Designated as safety issue: No ]
    Pain from VAS

Secondary Outcome Measures:
  • Quality of Life (QoL) [ Time Frame: 6 months ] [ Designated as safety issue: No ]

Other Outcome Measures:
  • kidney function [ Time Frame: 6 months ] [ Designated as safety issue: Yes ]
    creatinine clearance

Estimated Enrollment: 12
Study Start Date: February 2014
Estimated Study Completion Date: February 2015
Estimated Primary Completion Date: February 2015 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: immediate renal denervation
immediate renal denervation
Procedure: renal denervation
Active Comparator: delayed renal denervation
delayed renal denervation
Procedure: renal denervation


Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • Pain limiting daily activities in spite of pain killers, ADPKD

Exclusion Criteria:

  • Pregnancy
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT02062671

Contact: Hans Dieperink, MD +4520598851
Contact: Marie Blicher, MD + 45 65415305

Department of Nephrology Recruiting
Odense, Denmark, 5000
Contact: Hans Dieperink, MD    004520598851   
Principal Investigator: Hans Dieperink, MD         
Sponsors and Collaborators
Odense University Hospital
  More Information

Responsible Party: Hans Dieperink, Head of Department, MD, Odense University Hospital Identifier: NCT02062671     History of Changes
Other Study ID Numbers: RePKID  S-20130085 
Study First Received: February 12, 2014
Last Updated: February 13, 2014
Health Authority: Denmark: The Ethics Comitee for Southern Denmark

Keywords provided by Odense University Hospital:
renal denervation

Additional relevant MeSH terms:
Kidney Diseases
Polycystic Kidney Diseases
Polycystic Kidney, Autosomal Dominant
Kidney Diseases, Cystic
Urologic Diseases processed this record on May 26, 2016