The Impact of Storage Techniques on Platelets Number and Function After Acute Normovolemic Hemodilution (ANH)
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|ClinicalTrials.gov Identifier: NCT02060838|
Recruitment Status : Completed
First Posted : February 12, 2014
Results First Posted : March 31, 2017
Last Update Posted : March 31, 2017
|Condition or disease||Intervention/treatment|
|Cardiac Surgical Procedures||Procedure: Acute normovolemic hemodilution (ANH)|
|Study Type :||Observational|
|Actual Enrollment :||50 participants|
|Study Start Date :||March 2014|
|Actual Primary Completion Date :||September 2016|
|Actual Study Completion Date :||September 2016|
Acute normovolemic hemodilution (ANH)
Patients undergoing acute normovolemic hemodilution (ANH) as part of their cardiac surgery.
Procedure: Acute normovolemic hemodilution (ANH)
Blood is drawn from our patients pre-bypass after obtaining the arterial line and administered back to the patient after separation from cardiopulmonary bypass (CPB) and reversal of heparin with protamine.
- Time to Platelet Aggregation as Measured Using Collagen-epinephrine (EPI) [ Time Frame: Just prior to re-transfusion, assessed up to 5 minutes ]The membrane of the cartridges are coated with collagen and epinephrine (EPI) inducing a platelet plug to form which closes the aperture.
- Time to Platelet Aggregation as Measured Using Collagen-Adenosine (ADP) [ Time Frame: Just prior to re-transfusion, assessed up to 5 minutes ]The membrane of the cartridges are coated with collagen and adenosine diphosphate (ADP) inducing a platelet plug to form which closes the aperture.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02060838
|United States, Ohio|
|Nationwide Children's Hospital|
|Columbus, Ohio, United States, 43205|