Effect of Shisha Smoking on the Biology of the Airway Epithelium in Qatar
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|ClinicalTrials.gov Identifier: NCT02021708|
Recruitment Status : Completed
First Posted : December 27, 2013
Last Update Posted : April 29, 2016
|Condition or disease|
|Study Type :||Observational|
|Actual Enrollment :||64 participants|
|Official Title:||Effect of Shisha Smoking on the Biology of the Airway Epithelium in Qatar|
|Study Start Date :||January 2013|
|Actual Primary Completion Date :||January 2016|
|Actual Study Completion Date :||January 2016|
This group will include individuals without any history of lung disease, including asthma, and without recurrent or acute pulmonary disease. Individuals must also have smoked less than 100 cigarettes and/or less than 10 shisha pipes in their lifetime.
This group will include individuals who have a shisha smoking history of more than 5 pipe-years and must currently smoke more than 5 pipes per week. Individuals must not show any signs of acute lung infection or have medical history of significant illness or other significant medical issues.
This group will include individuals who have a cigarette smoking history that will be confirmed by urine testing. Individuals must not show any signs of acute lung infection or have medical history of significant illness or other significant medical issues.
- Gene expression changes in the small airway epithelium (SAE) [ Time Frame: 3 days ]We will measure the effect that shisha smoking has on the small airway epithelium (SAE) by measuring parameters such as the SAE gene expression in shisha smokers (i.e., non-cigarette smokers). We will compare these parameters to the same parameters measured in non-smokers and cigarette smokers.
Biospecimen Retention: Samples With DNA
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02021708
|Hamad Medical Corporation|
|Principal Investigator:||Matthew Walters, PhD||Weill Medical College of Cornell University|