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Prokinecitine in Acute Myocardial Infarction (Prok-Idm)

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
 
ClinicalTrials.gov Identifier: NCT02021487
Recruitment Status : Terminated (recruitment difficulty)
First Posted : December 27, 2013
Last Update Posted : August 21, 2019
Sponsor:
Information provided by (Responsible Party):
University Hospital, Strasbourg, France

Study Description
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Brief Summary:
The study aims to investigate the presence of a substance in the blood called prokinecitine, which is released by the heart when a heart attack occurs. Several venous blood samples at the arm are withdrawn at admission, H6, H12, H24, H48 and H72 in order to measure the concentration of this substance in the blood. The usefulness of this new blood marker is going to be determsined to seek if it would be of help to better diagnose or estimate the gravity of heart infarction after a heart attack.

Condition or disease
ST Elevatation Myocardial Infarction (STEMI)

Study Design
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Study Type : Observational
Actual Enrollment : 172 participants
Observational Model: Case-Control
Time Perspective: Prospective
Official Title: Pilot Study Prok-Idm: Interest of Dosage of Prokinecitine in Acute Myocardial Infarction
Actual Study Start Date : November 2013
Actual Primary Completion Date : February 2019
Actual Study Completion Date : February 2019

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Heart Attack

Groups and Cohorts
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Outcome Measures
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Primary Outcome Measures :
  1. Infarct size by MRI necrotic myocardial mass [ Time Frame: 7 days ]
    Infarct size by MRI necrotic myocardial mass


Eligibility Criteria
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Ages Eligible for Study:   18 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Patients with acute St elevation myocardial infarction of less than 6 hours
Criteria

Inclusion Criteria:

  • Patients with acute St elevation myocardial infarction of less than 6 hours
  • Age>18 y/o

Exclusion Criteria:

  • Previous myocardial infarction
  • LBB, RBB
  • Renal Insuffiency MDRD<30 mL/min
  • Patient with Pace-Maker or ICD.
Contacts and Locations
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Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02021487


Locations
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France
University Hospital
Strasbourg, France, 67000
Sponsors and Collaborators
University Hospital, Strasbourg, France
Investigators
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Principal Investigator: Patrick OHLMANN, MD University Hospital, Strasbourg, France
More Information
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Responsible Party: University Hospital, Strasbourg, France
ClinicalTrials.gov Identifier: NCT02021487    
Other Study ID Numbers: 5515
First Posted: December 27, 2013    Key Record Dates
Last Update Posted: August 21, 2019
Last Verified: August 2019
Additional relevant MeSH terms:
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Myocardial Infarction
Infarction
Ischemia
Pathologic Processes
Necrosis
 Myocardial Ischemia
Heart Diseases
Cardiovascular Diseases
Vascular Diseases