Cerebral Microembolism During Hemodialysis
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|ClinicalTrials.gov Identifier: NCT02021045|
Recruitment Status : Completed
First Posted : December 27, 2013
Last Update Posted : March 4, 2016
There is increasing evidence that renal replacement therapy (= continuous veno-venous hemodialysis) generates cerebral microembolism which is detectable on transcranial Doppler ultrasound.
The aim of this study is to monitor patients with transcranial Doppler under two conditions: during hemodialysis and in a hemodialysis-free interval (in each period cerebral embolic load is detected during 30 minutes).
The study hypothesis is that during hemodialysis the cerebral embolic load is significantly higher than in the hemodialysis-free interval.
|Condition or disease||Intervention/treatment|
|Complication of Dialysis Thrombus Due to Renal Dialysis Device, Implant, or Graft Cerebral Embolism||Device: Renal hemodialysis (Fresenius 2008K, Bad Homburg, Germany)|
|Study Type :||Observational|
|Actual Enrollment :||40 participants|
|Official Title:||Quantity, Quality and Laterality of Cerebral Microembolism During Veno-Venous Hemodialysis.|
|Study Start Date :||September 2013|
|Actual Primary Completion Date :||November 2015|
|Actual Study Completion Date :||March 2016|
Patient on Hemodialysis
Device: Renal hemodialysis (Fresenius 2008K, Bad Homburg, Germany)
Renal replacement therapy is frequently used in patients with renal failure in order to eliminate substances obligatory excreted by the urine.
Other Name: Continuous veno-venous hemodialysis
Patient in a hemodialysis-free interval
No Renal hemodialysis
- Quantity of cerebral embolic load [ Time Frame: 30 minutes ]Cerebral embolic load is measured in a 30 minutes-interval during hemodialysis and in a hemodialysis-free interval.
- Quality and laterality of cerebral embolic load [ Time Frame: 30 minutes ]Quality (solid vs. gaseous) and laterality (left vs. right hemispheric dominance) of cerebral embolic load is measured in a 30 minutes-interval during hemodialysis and in a hemodialysis-free interval.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02021045
|Medical University of Vienna|
|Vienna, Austria, 1090|
|Principal Investigator:||Gabor Erdoes, MD||Medical University of Vienna|