Working…
COVID-19 is an emerging, rapidly evolving situation.
Get the latest public health information from CDC: https://www.coronavirus.gov.

Get the latest research information from NIH: https://www.nih.gov/coronavirus.
ClinicalTrials.gov
ClinicalTrials.gov Menu

Incidence and Predictive Factor of Irritable Bowel Syndrome After Acute Diverticulitis in Korea

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
 
ClinicalTrials.gov Identifier: NCT02003807
Recruitment Status : Completed
First Posted : December 6, 2013
Last Update Posted : December 6, 2013
Sponsor:
Information provided by (Responsible Party):
Yonsei University

Brief Summary:
The pathogenesis of irritable bowel syndrome (IBS) is considered immune reaction of gastrointestinal tract. Therefore there is growing evidence that IBS could occur after gastroenteritis. However, little is known about the incidence of IBS after acute diverticulitis. We thought that post diverticulitis status could induce IBS because diverticulitis was also bowel inflammatory disorder. This survey was designed to identify incidence of post-diverticulitis IBS and risk factor in Korea.

Condition or disease
Diverticulitis and Irritable Bowel Syndrome

Layout table for study information
Study Type : Observational
Actual Enrollment : 102 participants
Observational Model: Case-Control
Time Perspective: Retrospective
Study Start Date : July 2013
Actual Primary Completion Date : September 2013
Actual Study Completion Date : September 2013

Resource links provided by the National Library of Medicine


Group/Cohort
Diverticulitis patients (case)
Cases were the patients who admitted to hospital because of acute diverticulitis attack.
Non-diverticulitis patients (control)
Controls were the patients who admitted to hospital due to non-gastrointestinal disorder.



Primary Outcome Measures :
  1. The newly developed IBS [ Time Frame: Survey was done from 15th July 2013 to 30th September 2013 ]
    The primary outcome was newly developed IBS. This was checked by telephone survey from 15th July 2013 to 30th September 2013. IBS was diagnosed by Rome III criteria.



Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.


Layout table for eligibility information
Ages Eligible for Study:   20 Years to 80 Years   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
Patients who had admitted Severance hospital, Seoul, South Korea.
Criteria

Inclusion Criteria:

  • 20 years or over
  • Patients who diagnosed diverticulitis by CT scan from 2006 to 2010 (Case)
  • Patients who admitted to hospital because of non-gastrointestinal disorder (Control)

Exclusion Criteria:

  • Patients who diagnosed IBS before diverticulitis (Case)
  • Patients who diagnosed IBS before admission (Control)
  • Patients with bowel resection surgery except for laparoscopic appendectomy
  • Pregnancy
  • Do not agree the consent of this study
  • Patients who dose not understand telephone survey such as foreigner, mental retardation.

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02003807


Locations
Layout table for location information
Korea, Republic of
Division of Gastroenterology, Department of Internal Medicine, Yonsei University College of Medicine
Seoul, Korea, Republic of, 120-752
Sponsors and Collaborators
Yonsei University
Additional Information:
Publications:

Layout table for additonal information
Responsible Party: Yonsei University
ClinicalTrials.gov Identifier: NCT02003807    
Other Study ID Numbers: 4-2013-0326
First Posted: December 6, 2013    Key Record Dates
Last Update Posted: December 6, 2013
Last Verified: December 2013
Additional relevant MeSH terms:
Layout table for MeSH terms
Diverticulitis
Irritable Bowel Syndrome
Syndrome
Disease
Pathologic Processes
Colonic Diseases, Functional
Colonic Diseases
Intestinal Diseases
Gastrointestinal Diseases
Digestive System Diseases
Diverticular Diseases
Intraabdominal Infections
Infection
Gastroenteritis