Jugular Venous Flow Healthy Volunteers
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|ClinicalTrials.gov Identifier: NCT02002494|
Recruitment Status : Completed
First Posted : December 5, 2013
Results First Posted : June 4, 2020
Last Update Posted : June 4, 2020
|Condition or disease||Intervention/treatment|
|Jugular Venous Blood Flow||Other: Different positions|
The different positions used in neurosurgery (park bench, prone) for better accessibility to the operating field can impact on the cerebral venous drainage due to the effects of internal jugular venous outflow of blood and may increase intracranial pressure. The kinking of the internal jugular vein due to excessive neck flexion and rotation in park bench or flexion in the prone position may lead to kinking or twisting of the vein. This has been hypothesized as the major cause of disturbed venous drainage during surgery and in postoperative patients may lead to neck swelling, brachial plexus injury, macroglossia (swollen tongue), delayed airway obstruction and increases in intracranial pressure.
Optimal brain perfusion is best in the neutral position of the head, but surgery cannot always be performed with this. Thus, we look to measure the internal jugular venous flow at different positions as there have been little studies looking at this important contributing factor.
|Study Type :||Observational|
|Actual Enrollment :||27 participants|
|Official Title:||Effect of Different Surgical Positions on the Cerebral Venous Drainage: an Ultrasound Study on Healthy Volunteers|
|Study Start Date :||June 2013|
|Actual Primary Completion Date :||February 2014|
|Actual Study Completion Date :||February 2014|
volunteers in different positions
The following will be compared in the same volunteer:
Other: Different positions
Jugular venous blood flow in healthy volunteers in 3 different positions- supine, prone and park bench
- Internal Jugular Venous (IJV) Cross Sectional Area [ Time Frame: 1 day ]Comparisons of both jugular vein (IJV) of twenty-seven volunteers in supine and prone positions.
- Right and Left IJV Cross Sectional Area [ Time Frame: 1 day ]Twenty-seven volunteers were included in this study. Comparisons of cross sectional area measurements in both IJVs between supine and right park bench
- Internal Jugular Venous (IJV) Doppler Velocity [ Time Frame: 1 day ]27 volunteers enrolled to measure the Internal Jugular Venous (IJV) in supine and prone positions
- Bilateral Internal Jugular Vein (IJV) Flow [ Time Frame: 1 day ]Comparisons of bilateral internal jugular vein (IJV) flow between supine and prone position. Data presented as mean (SD) .
- Bilateral Internal Jugular Vein (IJV) Doppler Velocity [ Time Frame: 1 day ]Comparisons of bilateral internal jugular vein (IJV) Doppler velocity between supine and right park bench position.
- R IJV and L IJV Flow [ Time Frame: 1 day ]Bilateral internal jugular vein (IJV) flow between supine and right park bench position.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02002494
|University Health Network, Toronto Western Hospital|
|Toronto, Ontario, Canada, M5T 2S8|
|Principal Investigator:||Lashmi Venkatraghavan||University Health Network, Toronto Western Hospital|
|Principal Investigator:||Vincent Chan||University Health Network, Toronto Western Hospital|
|Principal Investigator:||Pirjo Manninen||University Health Network, Toronto Western Hospital|
|Principal Investigator:||Audrey MY Tan||University Health Network, Toronto Western Hospital|