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Hypertension of Our Patients: Knowledge, Control, Comorbidity (H3C)

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT01998022
Recruitment Status : Completed
First Posted : November 28, 2013
Last Update Posted : October 3, 2014
Information provided by (Responsible Party):
Groupe Hospitalier de la Region de Mulhouse et Sud Alsace

Brief Summary:

Numerous studies highlight the insufficiency of blood pressure control in treated hypertensive population [1].

As shown in the MONICA study, increased cardiovascular mortality is found in Alsace compared to other french regions. The incidence and prevalence of diabetes and obesity are likely explanatory factors leading to this excess mortality [2].

Furthermore, the incidence and prevalence of alsacian patients with end-stage renal failure (ESRD) is also higher than the national average. The high prevalence of diabetes, hypertension and obesity in this population is also probably responsible for the high prevalence of ESRD [3].

Opportunities to prevent the progression of kidney disease involve an optimal control of treatable evolutionary factors.

Beyond control of diabetes and obesity, optimization of blood pressure control are an important factor to consider, as national and international guidelines recommend lower blood pressure targets in this population [4]. Knowledge of the disease and treatment goals are a key component of hypertensive patient management. Studies have shown that the knowledge of hypertensive disease and therapeutic targets were correlated with treatment compliance and with the rate of blood pressure control [5]. Patient education and participation of non-medical actors (nurses, pharmacists, …) are likely to improve the management and treatment compliance of these patients [6]. To our knowledge, no investigation has been performed in our region to determine the epidemiological characteristics, the knowledge level and blood pressure control in the population of hypertensive patients. The main objectives of this observational study are to evaluate, in a treated hypertensive population:

the knowledge level of the blood pressure treatment goals, the impact of patient knowledge on this blood pressure control, the potential impact of the patient's comorbidities on his blood pressure control.

Such a study should provide the basis for the feasibility of a large survey.

Condition or disease

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Study Type : Observational
Actual Enrollment : 383 participants
Time Perspective: Prospective
Official Title: Hypertension of Our Patients: Knowledge, Control, Comorbidity
Study Start Date : April 2013
Actual Primary Completion Date : December 2013
Actual Study Completion Date : January 2014

Resource links provided by the National Library of Medicine

Primary Outcome Measures :
  1. percentage of patients knowing the blood pressure target [ Time Frame: Patients are included for the time of form completion, an expected average of 15 minutes ]

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Treated hypertensive population

Inclusion Criteria:

  • Hypertensive patients moving spontaneously to their pharmacy to get their usual medications, including at least one drug in the class of anti-hypertensive

Exclusion Criteria:

  • Refusal or inability of the patient to respond to the questionnaire.
  • Antihypertensive therapy changed in the month preceding the survey.
  • Antihypertensive therapy initiated within three months preceding the survey.
  • Age <18 years.

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT01998022

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Mulhouse, France, 68100
Sponsors and Collaborators
Groupe Hospitalier de la Region de Mulhouse et Sud Alsace
Registre REIN Rapport annuel 2010
M Ashok Kumar. Improving medication adherence and clinical outcomes of hypertensive patients through patient counseling. Research Journal of Pharmaceutical, Biological and Chemical Sciences 2011; 2: 232-241

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Responsible Party: Groupe Hospitalier de la Region de Mulhouse et Sud Alsace Identifier: NCT01998022    
Other Study ID Numbers: 2013-A00207-38
651 ( Other Identifier: CHM )
First Posted: November 28, 2013    Key Record Dates
Last Update Posted: October 3, 2014
Last Verified: October 2014
Keywords provided by Groupe Hospitalier de la Region de Mulhouse et Sud Alsace:
blood pressure control
Additional relevant MeSH terms:
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Vascular Diseases
Cardiovascular Diseases